1. aplastic anemia - -bone marrow replaced with fat -caused by t cel...

NUR 339 Anemias

• aplastic anemia

Answer decrease number or damage to bone marrow stem cells and or bone marrow environment

-bone marrow replaced with fat -caused by t cell attacking the bone marrow rare life threatening infections and bleeding

• pancytopenia

Answer aplastic anemia results in .... low on all blood cells

-low reticulocyte count, normochromic, normocytic RBC's

• aplasia

Answer decrease RBC production causing severe anemia

• neutropenia

Answer low neutrophil count

• thrombocytopenia

Answer decreased platelets

• CBC and bone marrow biopsy

Answer aplastic anemia is diagnosed by ... findings show hypoplasia or aplastic bone marrow (few or no cells)

• aplastic anemia causes 1 / 2

Answer congenital idiopathic

secondary to drugs -antibiotics, antineoplastics/chemo, anticonvulsants -radiation therapy -chemicals 2/3 unknown may not have symptoms until signs of bone marrow failure

• bone marrow failure symptoms

Answer leukopenia- increased infections erythropenia anemia symptoms thrombocytopenia- bleeding, petechiae, and ecchymoses

• aplastic anemia symptoms

Answer bone marrow failure symptoms

• retinal hemorrhage common

-splenomegaly -lymphadenopathy- enlarged lymph nodes

• aplastic anemia treatment

Answer supportive care assess for and prevent bleeding and infection surgical Answer bone marrow transplant (under age 60 and healthy, provides a cure) immunosuppression

• immunosuppression on aplastic anemia

Answer prevent t cells from attacking bone marrow AE

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