NUR 405 Endocrine
- pathophysiology review
-hormones
-endocrine glands -function of hormones
- pituitary disorders
-acromegaly
-diabetes insipidus (DI) -syndrome of inappropriate antidiuretic hormone (SIADH)
- pituitary gland
-anterior pituitary gland
-posterior pituitary gland
- anterior pituitary gland
-thyroid-stimulating hormone (TSH) 1 / 4
-adrenocorticotropic hormone (ACTH) -growth hormone (GH)
- posterior pituitary gland
antidiuretic hormone (ADH or vasopressin)
- acromegaly
-caused by the oversecretion of growth hormone (GH) in adults
-results in enlargement of peripheral body parts and soft tissue without an increase in height
- acromegaly clinical manifestations
excessive skeletal growth in feet, hands, nose, chin and bones of the forehead and jaw
- acromegaly diagnostics
-labs
growth hormone (GH) suppression test
-imaging 2 / 4
skull x-ray, CT, or MRI
- diabetes insipidus (DI)
-caused by inadequate secretion of ADH (vasopressin)
-occurs as a result of...-results in...
-etiology
-central -nephrogenic -dipsogenic
- etiology of DI
central DI -head trauma
-surgery -infection -inflammation -brain tumors 3 / 4
-cerebral vascular disease -idiopathic
- etiology of DI
neprhogenic DI -kidney injury
-medications -hypokalemia -hypercalcemia
- etiology of DI
dipsogenic DI -defect in hypothalamus
-may be result of damage to the pituitary gland from head trauma, surgery, infection, inflammatory process, or tumor
- DI clinical manifestations
-significant daily output (greater than 250mL/hr) of very dilute urine
- / 4