NUR 325 Meds
- What are the 3 opioid receptors?
Answer mu, kappa, delta
- Adverse effects of Mu?
Answer Respiratory depression, euphoria, sedation, physical dependence
- Kappa adverse effects?
Answer Sedation, psychotomimetic effects
- Effects of delta?
Answer None
- What are the body's pain mediating chemicals?
Answer Bradykinins, histamine, prostaglandins, leukotrienes
- What are the 3 categories of pain relieving drugs?
Answer Nonopioid analgesics, opioid analgesics, opioid antagonists
- What does COX-1 do?
Answer Protect gastric mucosa, enhance platelet aggregation, promote renal function
- What does COX-2 do? 1 / 2
Answer Triggers inflammation, pain and fever
- First generation NSAIDS are both
Answer COX 1 and 2 inhibitors
- Effects of inhibiting cox-1?
Answer Gastric upset, heartburn, nausea, gastric ulcera- tion, bleeding tendencies, renal dysfunction
- Possible adverse effect of non-aspirin NSAID?
Answer Increased risk for throm- boembolic event
- What is salicylism?
Answer The buildup of aspirin to toxic levels
- What is Reye's syndrome?
Answer Rare disorder that occurs secondary to giving a child aspirin for a viral infection
- Symptoms of salicylism?
Answer Tinnitus and hearing loss, headache, dizziness
- What are the contraindications for aspirin?
- / 2
Answer Pregnancy, hypersensitivity to aspirin/NSAIDs, peptic ulcer disease or bleeding disorders, children with viral infec- tions, peri operative surgery