NUR 325 Drugs
- what are the therapeutic uses for aspirin and ibuprofen?
Answer inflammation sup- pression, analgesia for mild to moderate pain, fever reduction
dysmenorrhea, inhibition of platelet aggregation (aspirin)
- what are some of the adverse drug reactions for aspirin and ibuprofen?
Answer -
Gastric upset, heartburn. Nausea, gastric ulceration Bleeding Kidney dysfunction Salicylism (aspirin) Reye's syndrome (aspirin) Thromboembolic events (non-aspirin NSAID's)
- what are interventions for aspirin and ibuprofen?
Answer -monitor for GI bleeds, other signs of bleeding, I's and O's, tinnitus, diaphoresis, headache, dizziness, respiratory alkalosis, rises in BUN and creatinine, MI and CVA
-test for H pylori infection
- recommend
proton pump inhibitor for ppl at risk for GI bleeds, tylenol for children under 18 w viral infections, low dose for prevention of MI
- administration for aspirin and ibuprofen
Answer swallow EC tablets whole. discontin- ue 1 week before surgery
- client instructions for aspirin and ibuprofen
Answer -Take with food milk or water 1 / 2
-Avoid alcohol -Report signs of GI bleed or prolonged GI irritation -Report any unusual or prolonged bleeding -Report changes in weight, urine output or edema/fluid retention -Report chest pain, heaviness, shortness of breath, sudden and severe headache, numbness, weakness, visual disturbances, or confusion
- contraindications for aspirin and ibuprofen
Answer -Teratogenic
-Hypersensitivity to aspirin and other NSAID's, -peptic ulcer disease, -bleeding disorders -children or adolescents with influenza or chicken pox -perioperative use prior to coronary artery bypass grafting within 1 week of surgery
- precautions for aspirin and ibuprofen
Answer -Older adults
-Smoker -Alcohol use disorder -H pylori infection -Heart failure -hypertension -Hypovolemia
-Asthma -Chronic urticaria -Advanced kidney dysfunction
- interactions for aspirin and ibuprofen
Answer -Anticoagulants, glucocorticoids, and alcohol increase risk of bleeding
-Ibuprofen decreases antiplatelet effects of low-dose aspirin -ACE inhibitors and angiotensin receptor blockers increase the risk of kidney failure
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