AANP CERTIFIED NURSE PRACTITIONER

AANP CERTIFIED NURSE PRACTITIONER

(CNP) PRACTICE EXAM 1 QUESTIONS

AND CORRECT ANSWERS (VERIFIED

ANSWERS) PLUS RATIONALES 2025

• Which of the following medications is the first-line treatment for

uncomplicated hypertension in an African American patient without chronic kidney disease?

• Lisinopril
• Hydrochlorothiazide
• Atenolol
• Losartan

Answer: B) Hydrochlorothiazide

Rationale: Thiazide diuretics (like hydrochlorothiazide) and calcium channel

blockers are preferred first-line treatments for hypertension in African American patients without CKD, per JNC 8 guidelines.

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• A 25-year-old female presents with dysuria and urinary frequency. Which test

is most appropriate to confirm a urinary tract infection?

• Urine culture
• Urinalysis with dipstick
• Serum creatinine
• Abdominal ultrasound

Answer: B) Urinalysis with dipstick

Rationale: Urinalysis with dipstick is the initial, rapid test for UTI diagnosis, identifying leukocyte esterase and nitrites indicating infection.

• Which vaccine is contraindicated in pregnancy?
• Influenza (inactivated)
• Tetanus, diphtheria, and pertussis (Tdap)
• MMR (measles, mumps, rubella)
• Hepatitis B

Answer: C) MMR (measles, mumps, rubella)

Rationale: MMR is a live attenuated vaccine and contraindicated in pregnancy

due to risk of fetal harm.

• A patient presents with crushing chest pain radiating to the left arm. Which is

the most important immediate intervention?

• Administer aspirin
• Order a chest X-ray 2 / 3

• Start IV fluids
• Provide nitroglycerin

Answer: A) Administer aspirin

Rationale: Aspirin reduces platelet aggregation and mortality in suspected

myocardial infarction and should be given immediately unless contraindicated.

• Which lab value indicates diabetic ketoacidosis (DKA)?
• Serum glucose 120 mg/dL
• Serum bicarbonate 18 mEq/L
• Serum pH 7.25
• Serum potassium 3.0 mEq/L

Answer: C) Serum pH 7.25

Rationale: Acidosis (pH <7.3), hyperglycemia, and low bicarbonate are

characteristic of DKA.

• What is the recommended screening age for colon cancer in average-risk

adults?

• 40 years
• 45 years
• 50 years
• 55 years
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