AANP CERTIFIED NURSE PRACTITIONER
(CNP) PRACTICE EXAM 2 QUESTIONS
AND CORRECT ANSWERS (VERIFIED
ANSWERS) PLUS RATIONALES 2025
- A 45-year-old female presents with fatigue, weight gain, and cold intolerance.
Which laboratory test is most appropriate to evaluate her symptoms?
a) Complete blood count (CBC)
b) Thyroid-stimulating hormone (TSH)
c) Serum glucose
d) Liver function tests
Answer: b) Thyroid-stimulating hormone (TSH)
Rationale: Symptoms suggest hypothyroidism. TSH is the most sensitive test to
screen for thyroid dysfunction.
- Which vaccine is contraindicated in a pregnant woman?
a) Influenza (inactivated) 1 / 3
b) Tetanus-diphtheria-pertussis (Tdap)
c) Measles-mumps-rubella (MMR)
d) Hepatitis B
Answer: c) Measles-mumps-rubella (MMR)
Rationale: MMR is a live attenuated vaccine and contraindicated during
pregnancy due to potential teratogenicity.
- What is the first-line treatment for uncomplicated cystitis in a healthy adult
female?
a) Ciprofloxacin
b) Nitrofurantoin
c) Amoxicillin
d) Azithromycin
Answer: b) Nitrofurantoin
Rationale: Nitrofurantoin is effective, has low resistance rates, and is
recommended as first-line therapy for uncomplicated cystitis.
- A 65-year-old patient with hypertension presents with a blood pressure of
- <140/90 mm Hg
- <130/80 mm Hg
- <150/95 mm Hg
- <160/100 mm Hg 2 / 3
150/90 mm Hg. According to current guidelines, what is the target blood pressure?
Answer: b) <130/80 mm Hg
Rationale: Current ACC/AHA guidelines recommend a target of less than 130/80
mm Hg for most patients with hypertension.
- Which medication is contraindicated in a patient with asthma?
a) Albuterol
b) Metoprolol
c) Montelukast
d) Fluticasone
Answer: b) Metoprolol
Rationale: Beta blockers, especially non-selective types, can worsen
bronchospasm in asthma patients.
- What is the most common cause of acute pancreatitis?
a) Alcohol abuse
b) Gallstones
c) Hypertriglyceridemia
d) Medications
Answer: b) Gallstones
Rationale: Gallstones are the most common cause, followed by alcohol use.
- A patient with type 2 diabetes has an HbA1c of 9.5%. What is the next best
- / 3
step?