ABSITE LICENSE EXAM COMPLETE 450

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ABSITE LICENSE EXAM COMPLETE 450

QUESTIONS AND CORRECT DETAILED

ANSWERS (VERIFIED ANSWERS) |ALREADY

GRADED A+

• **2 weeks after a Whipple operation, your patient continues

to have early satiety with oral intake. You decide to start metoclopramide (Reglan) and erythromycin. What receptor does erythromycin bind to increase gastrointestinal motility?**

- **ANSWER:** Motilin (found primarily in the stomach,

duodenum, and colon)

- **Explanation:** The text states, "Motilin (found primarily

in the stomach, duodenum, and colon)," indicating that erythromycin binds to the motilin receptor to enhance gastrointestinal motility.

2. **Proteins are synthesized from:**

• **a.** mRNA
• **b.** tRNA
• **c.** dsDNA
• **d.** ssDNA

- **ANSWER:** a. mRNA

- **Explanation:** The text specifies, "mRNA," as the

template used in protein synthesis during translation.

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• **1 week after an APR, our patient develops urosepsis

requiring volume resuscitation, antibiotics, and moderate amounts of levophed and vasopressin. E. coli grows out from the blood cultures. What portion of the lipopolysaccharide complex accounts for its toxicity?**

- **ANSWER:** Lipid A (with gram-negative sepsis;

stimulator of TNFα)

- **Explanation:** The text states, "Lipid A (with gram

negative sepsis; stimulator of TNFα)," identifying Lipid A as the toxic component of the lipopolysaccharide in gram-negative bacteria like E. coli.

4. **Steroid hormones:**

• **a.** Bind a receptor on the plasma membrane and activate

a plasma membrane enzyme

• **b.** Bind a cytoplasmic receptor, enter the nucleus, and

affect transcription of proteins

• **c.** Bind a receptor in the nucleus and affect transcription

of proteins

• **d.** Do not enter the cell

- **ANSWER:** b. Bind a cytoplasmic receptor, enter the

nucleus, and affect transcription of proteins

- **Explanation:** The text specifies, "(b) Bind a receptor in

the cell cytoplasm, enter the nucleus as a steroid-receptor

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complex, and affect transcription of proteins," describing the mechanism of steroid hormone action.

• **4 days after an Ivor-Lewis esophagectomy, you decide to

start enteral tube feeding through a J-tube. The long chain fatty

acids contained in the tube feeds:**

• **a.** Enter the circulation via the portal system
• **b.** Enter the circulation via lymphatics
• **c.** Are only synthesized in the body
• **d.** Are not found in chylomicrons

- **ANSWER:** b. Enter the circulation via lymphatics

- **Explanation:** The text states, "(b) Long-chain FAs enter

the body through terminal lacteals (absorption through the lymphatic system) either as free LCFAs or as chylomicrons," confirming the lymphatic route for long-chain fatty acids.

• **Cells divide during what phase of the cell cycle?**
• **a.** G1
• **b.** S
• **c.** G2
• **d.** M

- **ANSWER:** d. M

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- **Explanation:** The text states, "(d) Cells divide during the

M phase (most radiosensitive)," indicating the mitotic (M) phase as the division phase.

• **Cell cycle length is determined by what phase of the cell

cycle?**

• **a.** G1
• **b.** S
• **c.** G2
• **d.** M

- **ANSWER:** a. G1

- **Explanation:** The text states, "(a) G1 ↔ G0 phase

determines cell cycle length (most variable cell period)," noting G1 as the most variable and thus determinant of cycle length.

• **Of the following, which is the most critical component in

the neovascularization of tumor metastases?**

• **a.** HER receptor
• **b.** VEGF receptor
• **c.** Neu receptor
• **d.** FGF receptor

- **ANSWER:** b. VEGF receptor