Advanced Pharmacology- FNP Exam Questions with Correct Answers 100% Verified 2024/2025 True or False: Children metabolize drugs faster than adults. - Correct Answer True which are easier to excrete: water soluble drugs or lipid soluble drugs? - Correct Answer Water soluble What are the cytochrome p450 inducers? (CRAPGPS) - Correct Answer Carbamazapine Rifampin Alcohol Phenytoin Griseofulvin Phenobarbital Sulfonylureas and St. Johns Wort what do CYP450 inducers do? - Correct Answer increase metabolism of drug, reduces drug level What are some examples of schedule 1 drugs? - Correct Answer heroin, LSD, marijuana What are some examples of schedule 2 drugs? - Correct Answer amphetamines, some opioids (morphine, meperidine, codeine) dronabinol, short-acting barbiturates what are some examples of schedule 3 drugs? - Correct Answer -Tylenol (acetaminophen) with codeine -Hydrocodone with acteaminophen (Vicodin, Loset, Lortab, Norco) -Various other codeine preparations (less than or equal to 1.8%) -Buprenorphine (Buprenex, Subutex, Suboxone) 1 / 2
What are some examples of schedule 4 drugs? - Correct Answer Benzodiazepine anxiolytics, muscle relaxers, and sedatives, pentazocine, ambien, klonipine What are some examples of schedule 5 drugs? - Correct Answer antidiarrheal, codeine used as antitussives, loperamide, lyrica, robitussin what is the first pass effect? - Correct Answer drugs absorbed from the GI tract enter the portal vein and pass through the liver before entering circulation.decreases bioavailability Where is drug absorption? - Correct Answer GI tract or blood vessels Where is drug distribution? - Correct Answer blood vessels Where is drug metabolism? - Correct Answer liver and kidneys Where is drug excretion? - Correct Answer Kidneys and GI tract What are free drugs? - Correct Answer drugs that are not bound to protein- exerts pharmacologic effect What does protein binding do to drug metabolism? - Correct Answer less pharmacologic effect in body What patients are at risk for reduced protein binding (increasing drug concentration)? - Correct Answer malnourished pregnant burn patients neonates
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