ALAT EXAM Study Guide Questions with Complete Solutions Name three types of institutions where an ALAT could work - Correct Answer public health organizations, research and teaching institutions, pharmaceutical and biological product companies List the three levels of AALAS Technician Certification - Correct Answer Assistant Laboratory Animal Technician, Laboratory Animal Technician, Laboratory Animal Technologist Other than the ALAT Manual, name the publications you must read and study to prepare for the exam - Correct Answer The Guide for the Care and Use of Laboratory Animals What organization was formed in 1950 by Dr. Nathan Brewer and other veterinarians? - Correct Answer Animal Care Panel In 1967, the Animal Care Panel (ACP) changed its name to this - Correct Answer American Association for Laboratory Animal Science List the two journals that are published by AALAS - Correct Answer JAALAS ( Journal of the American Association for Laboratory Animal Science) Comparative Medicine How do laboratory animal and research professional who are members of AALAS view the use of animals in research? - Correct Answer As a privilege What are two ways in which groups who oppose using animals in research express their opinions? - Correct Answer distribute pamphlets, lead protest demonstrations List five duties that are typically assigned to ALATs - Correct Answer cage cleaning, feed and watering, environmental and animal monitoring, record maintenance, room sanitation, public area maintenance, special assignments Role of PI - Correct Answer Plans and coordinates all phases of the research work and prepares the protocol Role of Research Tech - Correct Answer Performs research tasks required by the protocol and analyzes the data Role of Lab Animal Vet - Correct Answer Coordinates animal care and advises investigators on proper animal use Role of Lab Animal Tech - Correct Answer Performs many animal care functions and monitors environmental factors 1 / 3
Purpose of Guide for the Care and Use of Laboratory Animals - Correct Answer Primary source of the standards and guidelines for laboratory animal care and use in the US Purpose of Animal use protocol - Correct Answer A document written by the PI and approved by that IACUC that describes and justifies the use of animals for a project Purpose of PHS policy - Correct Answer Federal mandate that covers all live vertebrates used or intended for use in research, research training, experimentation, biological testing, or for related purposes Purpose of good laboratory practices - Correct Answer Regulations developed by the FDA and the EPA to validate and document the process of safety testing Purpose of standard operating procedure - Correct Answer Written instructions approved by management and used to perform a routine activity According to the Animal Welfare Act, list the three types of members who must sit on the IACUC - Correct Answer the chair, a vet, a non-affiliated member List five components of an animal care and use program for which the Guide describes standards - Correct Answer personnel qualifications and training, occupational health and safety, vet care, animal environment, animal procurement and transportation, surgical and post surgical care alleviation of pain and distress, euthanasia, physical plant design and construction Which of the following animals used in laboratory animal research would be covered by the Animal Welfare Act - Correct Answer Guinea pigs, rabbits, hamsters, ferrets, wild mice, horses, gerbils, goats, sheep The chapter lists some of the requirements in the Animal Welfare Act and the Animal Welfare Regulations if covered species are used. List five requirements - Correct Answer register with the USDA, appoint IACUC, provide training for animal users, maintain animal records, provide adequate vet care The appropriate use of analgesics in postsurgical animals would apply to which of the 3 Rs principles? - Correct Answer Refinement According to the Guide and PHS Policy, what document must institutions comply with when animals are euthanized? - Correct Answer AVMA Guidelines for Euthanasia List two common alternatives to using animals for research studies - Correct Answer Cell cultures, mathematical models 2 / 3
Beyond food, water, shelter, and healthcare requirements, the AWA and AWRs require that dogs have the opportunity for ______ and NHPS have ______ enrichment - Correct Answer exercise; psychological List three differences between the PHS Policy and the Animal Welfare act - Correct Answer PHS policy covers all vertebrates used in research, PHS policy has some administrative differences in its IACUC requirements, PHS policy requires an Occ Health and Safety program Function of the IACUC - Correct Answer An institutional body that oversees and evaluates an animal care and use program Function of Quality Assurance Unit - Correct Answer An institution unit that ensures compliance with the GLP Function of Animal & Plant Health Inspection Service - Correct Answer The body that administers and enforces the Animal Welfare Regulations Function of Association for the Assessment and Accreditation of Laboratory Animal Care International - Correct Answer A nonprofit organization that accredits laboratory animal research programs Function of Office of Laboratory Animal Welfare - Correct Answer The body that administers and enforces the PHS policy Using 100 mice in a research study instead of 150 would be an example of which of the
- Rs? - Correct Answer Reduction
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Some institutions may have to comply with PHS Policy but not animal welfare act. What are the factors that help determine which regulations are relevant to a particular research study - Correct Answer The species of animals used the funding sources Purpose of disaster plan - Correct Answer Provides steps for disaster preparedness and response Purpose of emergency contact list - Correct Answer Identifies whom to call if an emergency occurs Purpose of disaster drill - Correct Answer Measures the effectiveness of institution-wide emergency systems Purpose of post-incident discussion - Correct Answer Identifies ways to improve the disaster plan and emergency procedures Purpose of security plan - Correct Answer Describes ways to prevent and address security breaches