pg. 1 BOC Chemistry 6th Edition UPDATE ACTUAL EXAM
ALL QUESTIONS AND CORRECT DETAILED
ANSWERS.
Which of the following elevates carboxyhemoglobin?
- nitrite poisoning
- exposure to carbon monoxide
- sulfa drug toxicity
- sickle cell anemia - ANSWER - b
The reason carbon monoxide is so toxic is because it:
- is a protoplasmic poison
- comibines with cytochrome oxidase
- has 200 times the affinity of oxygen for hemoglobin binding sites
- sensitizes the myocardium - ANSWER - c
Cocain is metabolized to:
- carbamazepinne
- codeine
- hydrocodone
- benzoylecgonine - ANSWER - d
The metabolite 11-nor-etrahydrocannabinol-9-COOH- can be detected by immunoassay 3-5 days after a
single use of:
- methamphetamine
- cocaine
- benzodiazepine
- marijuana - ANSWER - d 1 / 4
pg. 2
A 3 year old child was evaluated for abdominal pain and anorexia by a physician. A CBC revealed a hemoglobin of 9.8 g/dL and basophilic stippling of the RBCs. The doctor should order further tests to
check for poisoning from:
- arsenic
- iron
- mercury
- lead - ANSWER - d
Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood
concentration of:
- lead
- mercury
- arsenic
- beryllium - ANSWER - a
A salicylate level is performed to detect toxicity caused by ingestion of excess:
- acetominophen
- aspirin
- ibuprofen
- pseudoephedrine - ANSWER - b
Testing for the diagnosis of lead poisoning should include:
- erythrocyte protoporphyrin (EPP)
- urine delta-aminolevulinic acid
- whole blood lead
- zinc protoporphryin (ZPP) - ANSWER - c
- / 4
pg. 3 Upon development of a thin layer chromatogram for the drug analysis, all drug spots (including the standards) had migrated with the solvent front. The most probable cause for this would be:
- environmental temperature too warm
- incorrect aqueous to non aqueous solvent mixture
- too much sample applied
- chromatogram dried too quickly - ANSWER - b
To detect barbiturate abuse when analyzing urine specimens, immunoassay is the method of choice for
screening. The method of choice for confirmation is:
- nephelometry
- thin-layer chromatography
- gas chromatography/mass spec
- ultraviolet absorption spectroscopy - ANSWER - c
Following overnight fasting, hypoglycemia in adults is defined as a glucose of:
- <70 mg/dL
- <60 mg/dL
- <55 mg/dL
- <45 mg/dL - ANSWER - c
The preparation of a patient for standard glucose tolerance testing should include:
- a high carbohydrate diet for 3 days
- a low carbohydrate diet for 3 days
- fasting for 48 days hour prior to testing
- bed rest for 3 days - ANSWER - a
If a fasting glucose was 90 mg/dL, which of the following 2-hour postprandial glucose results would most closely represent normal glucose metabolism?
- 55 mg/dL
- 100 mg/dL 3 / 4
pg. 4
- 180mg/dL
- 260 mg/dL - ANSWER - b
A healthy person with a blood glucose of 80 mg/dL would have a simultaneously determined
cerebrospinal fluid glucose value of:
- 25 mg/dL
- 50 mg/dL
- 100 mg/dL
- 150 mg/dL - ANSWER - b
A 25 year old man became nauseated and vomited 90 minutes after receiving a standard 75 g carbohydrate does for an oral glucose tolerance test. The best course of action is to:
- give the patient a glass of orange juice and continue the test
- start the test over immediately with a 50 g carbohydrate dose
- draw blood for glucose and discontinue test
- place the patient in a recumbent position, reassure him and continue the test - ANSWER - c
Cerebrospinal fluid for glucose assay should be:
- refrigerated
- analyzed immediately
- heated to 56 degrees C
- stored at room temperature after centrifugation - ANSWER - b
Which of the following 2-hour postprandial glucose values demonstrates unequivocal hyperglycemia diagnostic for diabetes mellitus?
- 160 mg/dL
- 170 mg/dL
- 180 mg/dL
- 200 mg/dL - ANSWER - d
- / 4