ANS: E DIF: 1 REF: P.18 OBJ: 5

Pathology for the Health Professions 4th Edition Damjanov Test Bank

Chapter 01: Cell Pathology

Test Bank

MULTIPLE CHOICE

1. All of the following are signs of irreversible cell injury except:

• Apoptosis
• Pyknosis
• Karyorrhexis
• Karyolysis
• Vacuolar degeneration

ANS: E DIF: 1 REF: P.18 OBJ: 5

2. Inhibition of ATP production by hypoxia causes all of the following except:

• Increased production of lactic acid in the cytoplasm
• Degranulation of the rough endoplasmic reticulum
• Dilation of the rough endoplasmic reticulum
• Swelling of the mitochondria
• Alkalinization of the hyaloplasm

ANS: E DIF: 1 REF: P.8 OBJ: 4

• Which of the following is an oxygen radical?
• Hydrogen peroxide
• Acid hydrolase
• ATP
• Carbon tetrachloride
• Lipofuscin

ANS: A DIF: 2 REF: P.10 OBJ: 6

• Which of the following organs undergoes atrophy during childhood and adolescence?
• Uterus
• Breasts
• Thymus
• Thyroid
• Adrenals

ANS: C DIF: 2 REF: P.12 OBJ: 8

5. Enlargement of the heart caused by hypertension is a result of:

• Hyperplasia 1 / 4

• Hypertrophy
• Atrophy
• Metaplasia
• Dysplasia

ANS: B DIF: 2 REF: P.14 OBJ: 9

• When irritated by chronic exposure to cigarette smoke, columnar bronchial epithelium

changes into stratified squamous epithelium. This change is an example of:

• Hypertrophy
• Hyperplasia
• Atrophy
• Metaplasia
• Degeneration

ANS: D DIF: 3 REF: P.14 OBJ: 10

• Chronic hemolysis is characterized by accumulation of an iron-containing brown pigment

in the cytoplasm of liver cells. This brown pigment is called:

• Melanin
• Tyrosin
• Hemosiderin
• Ceruloplasmin
• Bilirubin

ANS: C DIF: 3 REF: P.15 OBJ: 11

• Which type of necrosis is found in granulomas of tuberculosis?
• Coagulation necrosis
• Liquefactive necrosis
• Caseous necrosis
• Fat necrosis
• Fibrinoid necrosis

ANS: C DIF: 3 REF: P.17 OBJ: 15

9. Myocardial infarct represents a form of:

• Dystrophic calcification
• Metastatic calcification
• Fibrinoid necrosis
• Coagulation necrosis
• Wet gangrene

ANS: D DIF: 3 REF: P.17 OBJ: 15 2 / 4

10. Liquefactive necrosis typically occurs within an infarct of the:

• Heart
• Brain
• Liver
• Kidney
• Pancreas

ANS: B DIF: 3 REF: P.17 OBJ: 15

11. Hydropic changes are described as:

• An equal level of water inside and outside the cell
• A decrease of water in the cytoplasm
• An increase of water in the cytoplasm
• A result of irreversible cell injury
• An increase of cell energy from the mitochondria.

ANS: C DIF: 2 REF: P.8 OBJ: 5

12. All of the following are considered oligominerals except:

• Selenium
• Zinc
• Copper
• Magnesium
• Iron

ANS: E DIF: 1 REF: P.7 OBJ: 2

• Which of the following would not be considered a pathogenic mechanism for causing

cellular injury?

• Toxins
• Microbial pathogens
• Genetic disturbances
• Coagulation
• Hypoxia

ANS: D DIF: 2 REF: P.7 OBJ: 6

14. A fatty liver can be described as:

• Extracellular accumulation of intermediate metabolites
• Intracellular accumulation of intermediate metabolites
• Atrophy of the liver
• Extracellular accumulation of sodium
• Intracellular accumulation of sodium

ANS: B DIF: 3 REF: P.15 OBJ: 12 3 / 4

15. Metastatic calcification is associated with the:

• Heart
• Liver
• Brain
• Pancreas
• Kidney

ANS: E DIF: 3 REF: P.18 OBJ: 16

• / 4