Pharmacotherapeutics for Advanced Practice Nurse Prescribers Nurse practitioner prescriptive authority is regulated by who? - correct answerThe State Board of Nursing for Each State What is the benefits of having an APRN prescriber? - correct answerAPRN's care for patients more holistically and include patients in making decisions regarding their care What does clinical judgement in prescribing include? - correct answerFactoring in the cost of the particular What is included in the criteria for choosing and effective drug for a disorder? - correct answerConsulting nationally recognized guidelines for disease management NP's thrive under the new health-care reform because of what? - correct answerNP's have the ability to control care cost and improve patient outcome Nutritional intake and lab results reflect hypoalbuminemia; why is this important for prescribers? - correct answerThe Distribution of drugs to target tissues may be affected Drugs that have an significant first-pass effect what? - correct answerthey are rapidly metabolized by the liver and may have little if any desired action The route of excretion of a volatile drug will likely be? - correct answerLungs Medroxyprogesterone (Depo Provera) is prescribed IM to create storage reservoir of the drug. What are storage reserviors> - correct answerIncreased the length of time a drug is available and active Why is Cephalexin given every 8 hours? What knowledge of the drug does the NP know? - correct answerHalf Life 1 / 2
Azithromycin doing requires that the first day's doing be twice those of the other four day; This is considered a loading does. What is a loading dose? - correct answerRapidly actives drug levels in the therapeutic range The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is
the: - correct answerOnset of action
Phenytoin required that a trough level be drawn. When and why are peak and trough levels are done - correct answerTo determine if a d rug is in the therapeutic range Drugs that are receptor agonists may demonstrate what property? - correct answerConcentrations will produce an adverse effect Factors that affect gastric drug absorption include - correct answerLipid solubility of the drug Drugs that are receptors antagonists, such as beta-blockers, may cause what? - correct answerAn exaggerated response if abrupt discontinues
Drug administration via IV:
1) need to be lipid soluble in order to absorb easily 2) Begin distribution in the body immediately 3) Are easily absorbed if they are nonionized 4) May use pinocytosis to be absorbed - correct answerAre easily absorbed if they are nonionized What is the combination effect when a medication is added to a regimen for a synergistic effect? - correct answerGreater than the sum of the effects of each drug individually Which of the following statements about bioavailability is true?1) Bioavailability issues are especially important for drugs with narrow therapeutic ranges or sustained-release mechanisms.2) brands of a drug have the same bioavailability.
- / 2