APEA- GI Patho Questions and

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APEA- GI Patho Questions and Answers | Latest Version | 2025/2026 | Correct & Verified

What is the primary cause of peptic ulcer disease?

• Excessive alcohol intake

✔✔B. Helicobacter pylori infection

• Viral infection
• High-fiber diet

Which symptom is most common in patients with gastroesophageal reflux disease (GERD)?

• Diarrhea

✔✔B. Heartburn

• Abdominal bloating
• Vomiting

What is the gold standard test for diagnosing Helicobacter pylori infection?

• Serum antibody test

✔✔B. Endoscopic biopsy with urease testing 1 / 3

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• Stool antigen test
• Breath test

Which medication class is the first-line treatment for GERD?

• Antacids only
• Prokinetic agents

✔✔C. Proton pump inhibitors (PPIs)

• H2 receptor blockers

What is a common complication of untreated GERD?

• Appendicitis

✔✔B. Barrett’s esophagus

• Ulcerative colitis
• Cholecystitis

Which symptom is characteristic of ulcerative colitis?

• Right lower quadrant pain
• Constipation 2 / 3

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✔✔C. Bloody diarrhea

• Weight gain

What laboratory test is commonly elevated in acute pancreatitis?

• Amylase and lipase

✔✔B. Both amylase and lipase

• AST and ALT
• Alkaline phosphatase

Which of the following is the most common cause of chronic pancreatitis?

• Gallstones

✔✔B. Chronic alcohol use

• Viral hepatitis
• Hyperlipidemia

What is the typical presentation of cholelithiasis (gallstones)?

• Persistent left upper quadrant pain

✔✔B. Intermittent right upper quadrant pain after fatty meals

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