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APEA- Ortho Patho Questions and Answers | Latest Version | 2025/2026 | Correct & Verified
What is the hallmark symptom of rheumatoid arthritis?
- Joint pain relieved by activity
- Joint pain worsening with activity
- Sudden onset of joint swelling
✔✔B. Morning stiffness lasting more than 1 hour
Which lab test is most specific for diagnosing rheumatoid arthritis?
- Rheumatoid factor (RF)
- ESR (erythrocyte sedimentation rate)
- C-reactive protein (CRP)
✔✔B. Anti-cyclic citrullinated peptide (anti-CCP) antibodies
What is the most common joint affected by osteoarthritis?
- Wrist
- Elbow 1 / 3
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✔✔C. Knee
- Shoulder
Which symptom is typical of gout?
- Symmetrical joint involvement
- Chronic, low-grade joint pain
- Morning stiffness lasting several hours
✔✔B. Sudden onset of severe joint pain, often in the big toe
What is the first-line treatment for acute gout flare?
- Methotrexate
- Allopurinol
- Colchicine prophylaxis
✔✔C. NSAIDs
Which of the following is a common feature of ankylosing spondylitis?
- Distal joint arthritis
✔✔B. Chronic lower back pain improving with exercise 2 / 3
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- Rash on extensor surfaces
- Symmetrical small joint arthritis
What imaging finding is characteristic of osteoarthritis?
- Joint space narrowing and osteophyte formation ✔✔
- Bone erosions and juxta-articular osteoporosis
- Periarticular calcifications
- Soft tissue swelling without bone changes
Which of the following is a typical extra-articular manifestation of rheumatoid arthritis?
- Psoriasis
- Uveitis
- Raynaud’s phenomenon
✔✔B. Rheumatoid nodules
What lab abnormality is commonly elevated in active lupus erythematosus?
- C3 and C4 complement levels
- / 3
✔✔B. Anti-nuclear antibodies (ANA)