ASCP Hematology Exam-MLT 2023

ASCP Hematology Exam-MLT 2023 Questions and Answers 100% Verified

The light-colored zone adjacent to the nucleus in a plasmacyte is the:

• ribosome
• chromatin
• mitochondria
• Golgi area - Correct Answer D. Golgi area

The majority of the iron in an adult is found as a constituent of:

• hemoglobin
• hemosiderin
• myoglobin
• transferrin - Correct Answer A. hemoglobin

The main function of the hexose monophosphate shunt in the erythrocyte is to:

• reglate the level of 2,3-DPG
• provide reduced glutathione to prevent oxidation of hemoglobin
• prevent the reduction of heme iron
• provide energy for membrane maintenance - Correct Answer B. provide the level 2,3-

DPG

In order for hemoglobin to combine reversibly with oxygen, the iron must be:

• complexed with haptoglobin
• freely circulating in the cytoplasm
• attached to transferrin
• in the ferrous state - Correct Answer D. in the ferrous state

In which of the following disease states are teardrop cells and adnormal platelets most characteristically seen?

• hemolytic anemia
• multiple myeloma
• G-6-PD deficiency
• myeloid metaplasma - Correct Answer D. myeloid metaplasia

In the normal adult, the spleen acts as a site for:

• storage of red blood cells
• production of red blood cells
• synthesis of erythropoietin 1 / 2

• removal of imperfect and aging cells - Correct Answer D. removal of imperfect and

aging cells After removal of red blood cells from the circulation hemoglobin is broken down into:

• iron, porphyrin, and amino acids
• iron, protoporphyrin, and globin
• heme, protoporphyrin, and amino acids
• heme, hemoseridin, and globin - Correct Answer B. iron, protoporphyrin, and globin

Heinz bodies are:

• readily identified with polychrome stains
• rarely found in glucose-6-phosphate dehydrogenase deficient erythrocytes
• closely associated with spherocytes
• denatured hemoglobin inclusions that are readily removed by the spleen - Correct

Answer D. denatured hemoglobin inclusions that are readily removed by the spleen

Cells for the transport of O2 and CO2 are:

• erythrocytes
• granulocytes
• lymphocytes
• thrombocytes - Correct Answer A. erythrocytes

Erythropoeitin acts to:

• shorten the replication time of the granulocytes
• stimulate RNA synthesis of erythroid cells
• increase colony-stimulating factors produced by the B-lymphocytes
• decrease the release of marrow reticulocytes - Correct Answer B. stimulate RNA

synthesis of erythroid cells What cell shape is most commonly associated with an increase MCHC?

• teardrop cells
• target cells
• spherocytes
• sickle cells - Correct Answer C. spherocytes

Which of the following characteristics are common to hereditary spherocytosis, hereditary elliptocytosis, hereditary stomatocytosis, and paroxysmal nocturnal hemoglobinuria?

• autosomal dominant inheritance
• red cell membrane defects
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