BIO 299 Week 2 Quiz 1 Questions and Correct

BIO 299 Week 2 Quiz 1 Questions and Correct Answers Latest Update Guaranteed A+ A blood sample from a patient with a high titer cold agglutinin, which of the following results can occur in the presence of a cold agglutinin?

• increased MCV and decreased RBC
• increased MCV and normal RBC
• decreased MCV and increased MCHC

D. decreased MCV and RBC - Correct Answer: D. MCV and RBC

A characteristic morphologic feature in hemoglobin C disease is:

• macrocytosis
• spherocytosis
• rouleax formation

D. target cells - Correct Answer: D. target cells

A common source of interference in the cyanmethehemoglobin method is:

• hemolysis
• very high WBC count
• cold agglutinins

D. clumped platelets - Correct Answer: B. very high WBC count

A patient has a congenital nonspherocytic hemolytic anemia. After exposure to anti- malarial drugs, the patient experiences a severe hemolytic episode. This episode is characterized by red cell inclusions caused by hemoglobin denaturation. Which of the following conditions is most consistent with these findings?

• G-6-PD deficiency
• thalassemia major
• pyruvate kinase deficiency

D. paroxysmal nocturnal hemoglobinuria - Correct Answer: A. G-6-PD deficiency

A patient has a high cold agglutinin titer. Automated cell counter results reveal an elevated MCV, MCH, MCHC. Individual erythrocytes appear normal on a stained smear,

but agglutinates are noted. The appropriate course of action would be to:

• perform the RBC, Hgb, Hct determinations using manual methods
• perform the RBC determination by a manual method; use the automated results for

the Hgb and Hct

• repeat the determinations using a microsample of diluted blood
• repeat the determinations using a prewarmed microsample of diluted blood - Correct

Answer: D. repeat the determinations using a prewarmed microsample of diluted blood

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A patient has the following laboratory results:

RBC: 2.00 x 10^6/uL (2.00 x 10^12/L)

Hct: 24%

Hgb: 6.8 g/dL (68 g/L)

Reticulocytes: 0.8%

The mean corpuscular volume (MCV) of the patient is:

• 35 um^3 (35 fL)
• 83 um^3 (83 fL)
• 120 um^3 (120 fL)

D. 150 um^3 (150 fL) - Correct Answer: C. 120 um^3 (120 fL)

A red blood cell about 5 um in diameter that stains bright red and shows no central

pallor is a:

• spherocyte
• leptocyte
• microcyte

D. macrocyte - Correct Answer: A. spherocyte

A screening test for paroxysmal nocturnal hemoglobinuria is:

• heat instability test
• sucrose hemolysis
• osmotic fragility

D. dithionite solubility - Correct Answer: B. sucrose hemolysis

After removal of red blood cells from the circulation hemoglobin is broken down into:

• iron, porphyrin, and amino acids
• iron, protoporphyrin, and globin
• heme, protoporphyrin, and amino acids
• heme, hemoseridin, and globin - Correct Answer: B. iron, protoporphyrin, and globin

An enzyme deficiency assciated with moderate to sever hemolytic anemia after the patient is exposed to certain drugs and characteristized by red cell inclusions formed by

denatured hemoglobin is:

• lactate dehydrogenase deficiency
• G-6-PD deficiency
• pyruvate kinase deficiency

D. hexokinase deficiency - Correct Answer: B. G-6-PD deficiency

Cells for the trCorrect Answer:port of O2 and CO2 are:

• erythrocytes
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