BIOC 2300 Exam Questions with 100% Verified Correct Answers Which of the Biomolecules below is correctly paired with its major function?
A) Protein: Info coding
B) Nucleic Acid: energy storage
C)Polysaccharide: energy storage
D)None of the above - Correct Answer C) polysaccharides major role in energy storage and metabolism Which one of the four classes of biomolecule precursors always contains one of the other tree as part of its structure? - Correct Answer Nucleotides - contain monosaccharide (ribose or deoxyribose) When a non-polar substance is added to water, how do the molecules of water adjacent to the substance behave? - Correct Answer Water molecules adjacent to non polar substance are unable to participate in H bonding with the substance, and thus their orientation is limited to H-bonding with neighbouring water molecules, reflecting a loss of entropy.Under which of the following condition would a creation be spontaneous at all temperatures? - Correct Answer only guarantee of spontaneity at all temps is if H is negative and S is positive What type of bond is made between nucleotides in the DNA backbone? - Correct Answer Phosphodiester bonds Type of bond used to link Carbohydrates - Correct Answer Glycosidic bonds Type of bond used to link proteins - Correct Answer Peptide (amide) bonds Differences between DNA and RNA - Correct Answer 1)DNA contains deoxyribose and RNA contains ribose 2)Thymine base in DNA is replaced by uracil in RNA 3)DNA is double helix 4)RNA can catalyze reactions while DNA does not 1 / 2
SNP (single nucleotide polymorphism) - Correct Answer SNPs are single base variants that occur on average ever few hundred nucleotides
Mutations - Correct Answer Missense: substitution of an amino acid
Silent Mutations: no change in aa
Framshift: can in reading frame
Aspartic acid normally has a pK of 3.9. At which pH value would you expect about 90% of Asp to be in the negatively charge form?? - Correct Answer According to the Henderson-Hasselbalch equation, the value of log[A-]/[HA] is +1 when the ratio of [A-]/[HA] is 10 (100-90), meaning the pH is one unit above the pK (4.9)
Ionizable Amino Acids - Correct Answer Asp, Glu, His: -
Lys, Arg, Cys, Tyr: +
Protein structure - Correct Answer Primary: Order of amino Acids
Secondary: Local folding/structure
Tertiary: Folding of polypeptide chain
Quaternary: Folding of multiple polypeptide chains
hydrophobic amino acids - Correct Answer Ala, Leu, Ile, Val, Met, Trp, Phe, Pro Trp - Correct Answer largest amino acid Pro - Correct Answer only imino acid: side chain connected to NH group forces kink in chains (can't hydrogen bond) polar amino acids - Correct Answer ser, thr, asp, gly, cys, asn, gln, his, the, Gly - Correct Answer simplest amino acid, only non chiral amino acid Cys - Correct Answer provides cross-linking
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