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Biochemistry - C785 Module 2
1.carboxyl group: A -COOH group, found in organic acids.
2.amino group: a chemical group consisting of a nitrogen atom
bonded to two hydrogen atoms
3.Where are the hydrophobic amino acids found in the protein?: found in
the interior of the protein 4.What kind of bond connects a positively charged group and a
negatively charged group?: ionic bond
5.What type of reaction forms a peptide bond?: dehydration synthesis
6.What type of reactions breaks the peptide bond?: Hydrolysis reaction
7.Peptide bonds are in what structure?: Primary structure
8.Hydrogen bonds hold which structure together?: Secondary and tertiary
9.What amino acids are found on the exterior of the protein?: polar
amino acids
10.Two non-polar amino acids make what kind of interaction?:
Hydrophobic interactions
11.Non-covalent interactions between amino acid R groups:
hydrophobic, ionic and hydrogen bonds 12.What structure has a disulfide bond that holds together 2 subunits of
an enzyme?: quaternary structure
13.What structure has an Ionic interactions that hold together 4 different
subunits of a protein?: quaternary structure
14.What structure has an Ionic interactions that hold together 3 identical
polypeptides: quaternary structure 1 / 2
pts olypepti his level of onds ds as well as ct to form the
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15.non polar amino acids: hydrophobic bond, weak strength,
heat disru interaction
16.primary structure of protein: the amino acid sequence of
the p chain
17.secondary structure of protein: Hydrogen bonds are
involved in t structure and the amino and carboxyl groups (backbone) form these b
18.tertiary structure of protein: hydrogen, ionic and disulfide
bon hydrophobic interactions
19.quaternary structure of a protein: 2 or more polypeptides
intera protein
20.Fate of misfolded proteins: aggregation, degradation and refolding
21.What kind of interaction between misfolded protein leads to
aggrega- tion?: hydrophobic interaction
22.What kind of proteins take part in the process involving refolding?:
chap- erones 23.A diabetic patient is suffering from ketoacidosis has low blood pH.What bond or interaction is most likely to be disrupted within a patient's
hemoglo- bin?: hydrogen bonds and ionic interactions
24.A patient presents with a fever of 110 F. Which bond or interactions is most likely to be disrupted within a neuronal protein if the fever isn't
resolved quickly?: hydrophobic interactions
25.Frying an egg in a pan changes the egg white color, due to the protein ovalbumin, from translucent to white. Which bond or interaction is most
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