SUBSCRIBE
Bios 225 Midterm Exam
- Contains 3 billion base pair, mutations expected in human cell
- Mutation
- Which aspect of DNA replication is affected by the drug
- What effect would the drug have on a cell
- Why might this drug be useful in treating cancer
- How is DNA replication affected when fluorairacil is present
- Can you design another potential anti cancer drugs
- Ligase
- / 1
–Answer Tens of thousands
–Answer Changes to the sequence of nucleotide in DNA (can deactivate some errors in DNA replication)
–Answer Extending primers with DNA
–Answer Cell would replicate DNA very slowing, using DNA polymerase I instead of III
–Answer It will stop cancer cells from dividing
–Answer DNA polymeras- es stay attached but their ability to extend primers is negative affected
–Answer A drug that blocks DNA polymerase I would have the effect of preventing primer RNA replacement with DNA
–Answer Seals nicks