BIOS 260 Chapter 20 - semi-catabolic. catabolic. anti-metabolic. semi...

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BIOS 260 Chapter 20

• An antibiotic made by microorganisms and modified by chemists is called

semi-catabolic. catabolic.anti-metabolic. semi-synthetic.synthetic.–Answer semi-synthetic.

• Beta-lactam drugs are only effective against growing bacteria. True or False

–Answer True

• Which is the correct definition of selective toxicity?

The range between the therapeutic dose and the toxic dose of a medication. A medication causing greater harm to a host than to a pathogen.A medication causing greater harm to a pathogen than to the host. The lowest dose of a medication toxic to the pathogen.A medication that only targets Gram-negative bacteria.–Answer A medication causing greater harm to a pathogen than to the host.

• The first example of an antimicrobial drug synthesized in the laboratory was

Salvarsan. erythromycin. Erlichsan. penicillin.sulfa.–Answer Salvarsan.

• Folic acid is ultimately used in the synthesis of

–Answer coenzymes

• What are two advantages of automated tests used to determine antimicro- bial

susceptibility? 1 / 2

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They produce results more quickly than conventional tests. They take longer to perform BUT they give fewer false results.They are cheaper than conventional tests AND they give more accurate results.They are easier to perform.They produce results more quickly than conventional tests AND they are easier to perform.–Answer They produce results more quickly than conventional tests AND they are easier to perform.

• Antimicrobial resistance can be due to spontaneous mutation or gene acquisition.

True or False –Answer True

• An elderly patient comes to see you complaining of a very painful rash. When he lifts his

shirt, you see that he has a rash of small blisters (vesi- cles) on one side of his back. You think he likely has shingles, caused by varicella-zoster virus (VZV), a double-stranded DNA virus that belongs to the Herpesviridae family. You explain this to your patient, who asks you to please give him an antibiotic for his infection. You tell him an antibiotic will not help him, and give him information on virus infections and their treatment.

Antibiotics are effective in treating viral infections provided that they are given early in the course of illness.True or False –Answer False

• The minimum bactericidal concentration is the lowest concentration of a specific

antimicrobial drug that kills % of a specific type of bacte- ria.–Answer 99.9%

• Inhibitors of protein synthesis typically act on

transfer RNA. porin proteins.

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