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BIOs 260 Midterm Exam
- Biology before Darwin
- predictable development
- darwin vs mendel
- how can mendel explain darwin's variation
- why is it not helpful to sequence the genome of one individual
- what causes cystic fibrosis
- what is an allele
- what determines CF disease phenotype
–Answer like physics
–Answer idea that if you can understand the way one chick develops you can understand them all
–Answer darwin = variation exists mendel = variation is discrete
–Answer additive alleles (no dominance)
–Answer irrelevant when the person dies variation that exists changes with each generation
–Answer defect in chloride transporter causes mucous blocking airways in lungs can arise in many different ways
–Answer variation of a gene
–Answer 1 / 2
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allele combinations
- drugs that resolve CF
- what is a gene
- what did Morgan believe about genes
- what is recombination
- McClintock experiment
- F1s crossed and meiotic products observed knob +
- genetic distance formula
- how to calculate the number of recombinants
- / 2
–Answer potentiator - restores channel gating stabilizer - decreases surface protein turnover corrector - improves protein folding + trafficking read-through - suppresses premature stop codons amplifier - stabilizes mRNA
–Answer function unit heredity that is responsible for a phenotype
–Answer they are all on the X chromosome
–Answer new combinations of genes
–Answer exoradiated chromosomes to make them morpholog- ically distinct (parent 1 = hook; parent 2 = knob)
hook associates with specific genes
–Answer (number of recombinants / total number of progeny) x 100 done with the F2 generation
–Answer Recombinants = NDP + 1/2 TT