pg. 1 Clinical Chemistry 2024 Final Test Bank Complete Actual Exam Questions with Correct Detailed Answers (Verified Answers) Rated A+ (Newest 2024 -2025)
Which of the following substances is administered to a patient with a long prothrombin time (PT) to determine if the cause is liver malfunction or malnutrition?
- Ascorbic acid
- Vitamin K
- Vitamin E
- Warfarin - Correct Answer - B. Vitamin K
Which of the following proteins has a half-life of approximately 20 days and decreased concentrations in serum are indicative of liver disease?
- Albumin
- Alkaline phosphatase
- Prealbumin
- Aspartate aminotransferase
- Prothrombin - Correct Answer - A. Albumin
ALP is used to diagnose hepatobiliary disorders because bile accumulation causes liver cells to synthesize more ALP, which then leaks into the serum.Which of the following is NOT true about ALP function liver test?
- 4xULN suggests a cholestatic disorder, but needs confirmation 1 / 4
pg. 2
- ALP can be found in many body tissues including liver, bone, and
- ALP test is based on an immunoassay and is diagnostic/specific for liver
- Additional tests to confirm a cholestatic cause of an ALP increase may
placenta
injury
include 5-NT and GGTP - Correct Answer - C. ALP test is based on an immunoassay and is diagnostic/specific for liver injury
Which test is NOT used to detect acute liver injury/changes?
- Prealbumin
B. AST
C. ALT
- Albumin - Correct Answer - D. Albumin (half-life is too long = 20 days, so
cannot measure ACUTE liver injury)
Which test is most specific for liver injury?
A. AST
B. ALT
C. ALP
- Total bilirubin
- LDH - Correct Answer - B. ALT
Which test is indicative of cholestatic liver disease?
- Elevation of total bilirubin and indirect bilirubin with normal ALT and AST
- Elevation of total bilirubin and direct bilirubin with normal ALT and AST
- Elevation of total bilirubin, ALT, and AST. - Correct Answer - B. Elevation
of total bilirubin and direct bilirubin with normal ALT and AST 2 / 4
pg. 3 Cholestatic liver disease does not have increase in ALT and AST. Direct bilirubin is synthesized from the indirect bilirubin by the conjugation reaction. When you have cholestatic liver disease, bile flow is abnormal, so you will have accumulation of direct bilirubin in the liver.
Which of the below is considered the primary toxin generated by the liver following alcohol ingestion that is believed to be the causes of alcoholic liver disease?
- Lactic acid
- Acetaldehyde
- Glutathione
- Methanol
- Ascorbic aci - Correct Answer - B. Acetaldehyde
(T/F) Unconjugated bilirubin (indirect) is insoluble in aqueous conditions and cannot be directly detected by the van der Bergh reaction. Conjugated bilirubin is formed in the liver by UGT1A1-catalyze glucuronidation and can be detected by the van der Bergh reaction. - Correct Answer - True
Which of the following statements is correct?
- Testosterone is involved in preparation of uterus for pregnancy and its
- Decreased levels of progesterone are associated with threat of
- Amenorrhea is the normal beginning of menses
- Increased levels of progesterone cause Virilization in women - Correct
- / 4
maintenance during pregnancy
spontaneous abortion and hyperprolactinemia
Answer - B. Decreased levels of progesterone are associated with threat of spontaneous abortion and hyperprolactinemia
pg. 4 Which of the following is not increased during hepatitis infection?
- Serum albumin
- Bilirubin
- Gamma globulin
D. ALT
E. AST
- Gamma-glutamic transpeptidase (GGTP) - Correct Answer - A. Serum
albumin
Which of the following statements is correct?
- Decreased levels of LH occur in pituitary adenomas and eating disorders
- Midcycle surge of LH causes menses
- Increased levels of LH can indicate PCOS
- FSH is stored in the ovaries - Correct Answer - A. Decreased levels of
- Increased levels of LH can indicate PCOS
LH occur in pituitary adenomas and eating disorders And
Which one of the following statements is correct?
- Decreased levels of FSH indicate correctly functioning ovaries
- FSH is stored in the thymus
- FSH levels decrease at puberty
- Increased levels of FSH indicate ovarian failure - Correct Answer - D.
Increased levels of FSH indicate ovarian failure
Which of the following type of bacteria have an outer membrane composed of lipopolysaccharide (LPS)?
- / 4