CMN 568 Unit 3 Questions with 100% Verified Correct Answers 2024/2025 What are the 3 characteristics of Asthma - Correct Answer Bronchoconstriction Airway Inflammation Reversible airflow limitation Which inhaled anticholinergic is best used for asthma pt. w/an intolerance to beta agonist or w/ bronchospasms due to beta blocker meds? - Correct Answer Ipratropium Bromide What is the primary tx for pt. w/moderate to severe asthma exacerbations who do not respond promptly and completely to SABA? - Correct Answer Systemic Corticosteroids Which bacterial infections predispose exacerbations of asthma - Correct Answer M. Pneumoniae and
- Pneumoniae
Is routine use of antimicrobials recommended for acute exacerbations of asthma - Correct Answer No, only use when likelihood of acute bacterial respiratory tract infection Name short acting beta agonist - Correct Answer albuterol, levalbuterol, bitolerol, pirbuterol, terbutaline What does a SABA do? - Correct Answer acts directly by relaxing bronchial smooth muscles.What do long-term pharmacologic agents accomplish for asthma pt. - Correct Answer act primarily to attenuate airway inflammation.Why take long-term pharmacologic agents for asthma daily? - Correct Answer to achieve and maintain control of persistent asthma independent of symptoms.What does the NAEPP recommend as the cornerstone of daily treatment of persistent asthma? - Correct Answer daily anti-inflammatory therapy with inhaled corticosteroids 1 / 3
Role of corticosteroids with asthma - Correct Answer Reduce inflammation (acute and chronic) = improved airflow, decreased airway hyper-responsiveness and fewer asthma exacerbations, and potentiate the action of beta-adrenergic agonist.1st. line treatment agent for all pt w/persistent asthma (long term controller) - Correct Answer Inhaled Corticosteroids How often to most patient use inhaled corticosteroids? - Correct Answer Twice daily to provide adequate control.How long can it take to see maximum response of inhaled corticosterioids? - Correct Answer Months What can a patient do to reduce side effects of inhaled corticosteroids? - Correct Answer Rinse mouth after each use A patient has an exacerbation of asthma, what is the most effective treatment to achieve prompt control? - Correct Answer Systemic (oral) corticosteroids Dose of oral corticosteroids for children during exacerbation of asthma - Correct Answer 1-2 mg/kg/day.Can be either a single dose or divided BID.MAX 60 mg/day Dose of oral corticosteroids for adults during exacerbation of asthma - Correct Answer 40-60 mg/day either as a single dose of divided BID Duration of treatment of oral corticosteroids for asthma exacerbation - Correct Answer 3-10 days or until symptoms resolve (no evidence that tapering dose of PO steroids prevents relapse) When treating exacerbation of asthma, what is the preferred treatment plan? - Correct Answer Alternate days rather than daily treatment. 2 / 3
What additional medications are required to be given concurrent with systemic corticosteroids to prevent corticosteroid induced bone mineral loss? - Correct Answer Vitamin D and Calcium Should systemic corticosteroids be rapidly discontinued? - Correct Answer No, to prevent adrenal insufficiency Name some mediator inhibitors to treat asthma - Correct Answer Cromolyn sodium and nedocromil What is the mechanism of action of mediator inhibitors? - Correct Answer prevent asthma symptoms, improve airway function in pt w/mild persistent of exercise induce asthma When are mediator inhibitors effective? - Correct Answer Before allergen exposure or exercise Do not relieve asthmatic symptoms once present.Name the Long acting beta 2 agonist (LABA) for asthma - Correct Answer Salmeterol and Formoteol How are LABA's delivered? - Correct Answer dry powder What are LABA's used for - Correct Answer Long term prevention of asthma symptoms Nocturnal symptoms Prevention of exercise induced bronchospasm Should LABA be used as monotherapy - Correct Answer NO linked to fatal asthma when used alone has no anti-inflammatory effects- so use w/a corticosteroid.What does LABA + low or medium dose of corticosteroids given together provide for the patient. - Correct Answer The equivalent to what would be if doubled the inhaled corticosteroid.Name the action of anticholinergic agents, short acting muscarinic agents (SAMA) and long acting muscarinic agents (LAMA) - Correct Answer Reverse vagally medicated bronchospasm but NOT allergen or exercise induced broncospasms
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