COMPLETE SOLUTIONS - COMPLETE SOLUTIONS Question 1: What type of ser...

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Blood Bank ASCP EXAM| 452 QUESTIONS| WITH

COMPLETE SOLUTIONS

Question 1: What type of serological testing does the blood bank

technologist perform when determining the blood group of a patient?

CORRECT ANSWER : phenotyping

Question 2: If anti-K reacts 3+ with a donor cell with a genotype

KK and 2+ with a Kk cell, the antibody is demonstrating:

CORRECT ANSWER : Dosage

Question 3: Carla expresses the blood group antigens Fya, Fyb,

and Xga. James shows expressions of none of these antigens.What factor(s) may account for the absence of these antigens in James?

CORRECT ANSWER : Gender and Race. The frequency of

Duffy antigens Fya and Fyb varies with race. The Fy(a−b−) phenotype occurs in almost 70% of African Americans and is very rare in whites. The Xga antigen is X-linked and, therefore, expressed more frequently in women (who may inherit the antigen from either parent) than in men.

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Question 4: Which of the following statements is true?

• An individual with the BO genotype is homozygous for B

antigen

• An individual with the BB genotype is homozygous for B

antigen

• An individual with the OO genotype is heterozygous for O

antigen

• An individual with the AB phenotype is homozygous for A

and B antigens

CORRECT ANSWER : B. An individual with the BB genotype

is homozygous for B antigen

Question 5: Which genotype is heterozygous for C?

• DCe/dce

B. DCE/DCE

• Dce/dce
• DCE/dCe

CORRECT ANSWER : A. DCe/dce

Question 6: Which genotype(s) will give rise to the Bombay

phenotype?

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The Bombay phenotype will be expressed only when no H substance is present. The Oh type is expressed by the genotype hh. Bombays produce naturally occurring anti-H, and their serum agglutinates group O red cells in addition to red cells from groups A, B, and AB persons.

CORRECT ANSWER : hh

Question 7: Meiosis in cell division is limited to the ova and

sperm producing four gametes containing what complement of DNA?

CORRECT ANSWER : 1N. Meiosis involves two nuclear

divisions in succession resulting in four gametocytes each containing half the number of chromosomes found in somatic cells or 1N.

Question 8: A cell that is not actively dividing is said to be in:

CORRECT ANSWER : Interphase, The cell is engaged in

metabolic activity. Chromosomes are not clearly discerned; however, nucleoli may be visible

Question 9: Which of the following describes the expression of

most blood group antigens?

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CORRECT ANSWER : Codominant

Question 10: What blood type is not possible for an offspring of

an AO and BO mating?

CORRECT ANSWER : All are possible

Question 11: The alleged father of a child in a disputed case of

paternity is blood group AB. The mother is group O and the child is group O. What type of exclusion is this?

CORRECT ANSWER : -Indirect/secondary/second order An

indirect/secondary/second order exclusion occurs when a genetic marker is absent in the child but should have been transmitted by the alleged father. In this case, either A or B should be present in the child.

Question 12: If the frequency of gene Y is 0.4 and the frequency

of gene Z is 0.5, one would expect that they should occur together 0.2 (20%) of the time. In actuality, they are found

together 32% of the time. This is an example of:

CORRECT ANSWER : Linkage disequilibrium. Linkage

disequilibrium is a phenomenon in which alleles situated in close proximity on a chromosome associate with one another