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CSAM EXAM NEWEST 2025 /CSAM
STUDYGUIDE ACTUAL EXAM COMPLETE ALL
400 QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+ (BRAND NEW VERSION!!)
- What is Cyproheptadine?
ANSWER: A 5-HT2A receptor antagonist
- What causes serotonin syndrome?
ANSWER: Excessive stimulation of 5-HT2A receptors and
possibly 5-HT1A receptors
- In patients withdrawing from both hypnotic-sedatives and
CNS stimulants, which is treated first?
ANSWER: Hypnotic-sedatives
- For patients on both opiates and sedative-hypnotics, which
should be tapered first?
ANSWER: Sedative-hypnotics should be tapered first while
keeping the opiate dose stable, followed by tapering the opiate once off the sedative-hypnotic
- Which enzyme metabolizes codeine into morphine?
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ANSWER: CYP2D6
- Which enzyme primarily metabolizes methadone?
ANSWER: CYP3A4
- Name some drugs that inhibit CYP3A4, slowing the
elimination of methadone and increasing its level.
ANSWER: Erythromycin, diltiazem, ketoconazole, and
saquinavir
- Name some drugs that induce CYP3A4, speeding up the
elimination of methadone and decreasing its level.
ANSWER: St. John’s wort, carbamazepine, phenobarbital,
efavirenz
- How can cocaine-induced psychosis be distinguished from
acute schizophrenia?
ANSWER: Tactile hallucinations and fewer negative
symptoms suggest cocaine-induced psychosis; more bizarre thinking suggests acute schizophrenia
- What is pharmacodynamics?
ANSWER: What the drug does to the body
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- What is pharmacokinetics?
ANSWER: What the body does to the drug
- How much alcohol does one standard alcoholic drink in the
United States contain?
ANSWER: 0.6 oz (17 g)
- What is an AWOL machine?
ANSWER: A device that allows inhalation of ethanol vapor
(Alcohol Without Liquid) for a quicker response
- Where is about 90% of alcohol absorbed in the body?
ANSWER: Jejunum
- How do alcohol levels differ between men and women of the
same weight consuming the same amount?
ANSWER: A woman will have a 20 to 25% higher blood
alcohol level than a man due to a lower rate of absorption in the stomach, despite most absorption occurring in the jejunum
- Describe how alcohol is broken down in the liver.
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ANSWER: Alcohol is converted to acetaldehyde by ADH and
CYP2E1, then acetaldehyde is converted to acetate by ALDH
- How does alcohol affect dopamine neuron firing in the
VTA?
ANSWER: Increases it
- How does alcohol’s mechanism in the body differ from
cocaine, amphetamine, benzodiazepines, or opiates?
ANSWER: Alcohol works on a diverse assortment of ligand-
gated and voltage-gated ion channels regulating neuronal excitability, whereas the others act on specific protein receptors on brain neurons
- What is the action of Flumazenil (Romazicon)?
ANSWER: A GABA-A receptor antagonist without intrinsic
activity
- What is the approximate rate of alcohol metabolism in the
average adult, proportional to bodyweight and likely liver weight?
ANSWER: 1 oz every 3 hours, or 28 g every 3 hours, or 9.4
g/hr