Final Exam Guide: NUR100 / NUR
100 (Latest 2024 / 2025 Update) Pharmacology | Guide with Questions and Verified Answers | 100% Correct | Grade A – Fortis
Question:
Antidepressant Drugs
Answer:
Indicated for major depressive disorders
Other indications:
Dysthymia (chronic low-grade depression)
As adjunct for schizophrenia
Eating disorders
Personality disorders
Various medical conditions 1 / 4
Migraine headaches Chronic pain/sleep disorders Premenstrual syndrome Hot flashes associated with menopause
Question:
Antidepressants
Answer:
Increase the levels of neurotransmitter concentration in CNS
Based on several hypotheses Biogenic amine hypothesis Permissive hypothesis Dysregulation hypothesis
Requires at least 6 weeks of therapy with adequate doses to be able to fully evaluate results
May require upward titration of dosages over several weeks
Should be used in conjunction with psychotherapy
Higher risk of suicide among both adult and pediatric population
- / 4
Tricyclic antidepressants
Monoamine oxidase inhibitors (MAOIs)
Second-generation antidepressants SSRIs Serotonin-norepinephrine reuptake inhibitors (SNRIs)
Question:
Suicidal thoughts
Answer:
When patients are taking selective SSRIs for the first time for depression, which is most important to monitor for during the first few weeks of therapy?
Question:
Tricyclic Antidepressants (TCA)
Answer:
Have largely been replaced by SSRIs as first-line antidepressant drugs
Considered second line
For patients who fail with SSRIs or other newer generation antidepressants
- / 4
As adjunct therapy with newer generation antidepressants
Amitriptyline (Elavil)
Question:
Tricyclic Antidepressants: Mechanism of Action
Answer:
Block reuptake of neurotransmitters, causing accumulation at the nerve endings
It is thought that increasing concentrations of neurotransmitters will correct the abnormally low levels that lead to depression.
Question:
Tricyclic Antidepressants: Indications
Answer:
Depression
Childhood enuresis (imipramine)
OCDs (clomipramine)
- / 4