NR-546 Advanced Pharmacology Psychopharmacology for the Psychiatric- Mental Health Nurse Practitioner
Final Exam (Latest Update)
Question:
SSRI MOA
Answer:
inhibit 5HT reuptake first line of treatment for depression
Question:
SSRI s/e
Answer:
- S's of SSRIs
- Stomach
- sexual dysfunction
- serotonin syndrome
- sleep difficulties
- suicidal thoughts 1 / 4
- stress
- size (weight)
Question:
serotonin s/e
Answer:
head, red, fed head = decreased anxiety, impulsivity, sex drive red = platelets and bleeding fed = gi motility and nausea
Question:
SSRI pt education
Answer:
most adverse affects will subside after 4-5 days once body adjusts to increased serotonin levels
Question:
SSRI drugs
Answer:
citalopram fluoxetine 2 / 4
paroxetine sertraline fluvoxamine bupropion
Question:
citalopram
Answer:
*has a mild antihistamine effect *causes QT prolongation citalopram = celexa, think of cel LEXUS (car) = car - get an electrocardiogram if on this drug
Question:
escitalopram
Answer:
*no known drug interactions, used with polypharmacy *best tolerated SSRI *27-32 hr half life
Question:
fluoxetine 3 / 4
Answer:
*longest half life - prescribe to patient who may forget to take their meds THINK fluoxetine - when you spent a long week in bed with the FLU (referring to the long half life) *use with caution if pt has comorbid anxiety due to risk of activation and panic attacks
Question:
paroxetine
Answer:
*also treats social anxiety disorder *highest risk of discontinuation syndrome due to serotonin transporter inhibition and anticholinergic rebound *patient will experience withdrawal symptoms if with a missed dose or late dose *contraindicated in pregnancy due to risk of congenital defects *avoid in hx of falls/fractures *associated with weight gain
Question:
sertraline
Answer:
*treats social anxiety *27-36 hr half life
- / 4