NR-546 Advanced Pharmacology Psychopharmacology for the Psychiatric- Mental Health Nurse Practitioner
Final Exam (Latest Update)
Question:
Medication Management
Answer:
SSRI-Selective Serotonin Reuptake Inhibitors *Inhibit 5 HT reuptake SNRI-Serotonin Norepinephrine Reuptake Inhibitors *inhibit 5-HT reuptake *inhibit NE reuptake (increase energy, focus) *increase DA in prefrontal cortex (increase cognition) NDRI-Norepinephrine Dopamine Reuptake inhibitors *inhibit DA reuptake (increase alertness, motivation) *inhibit NE reuptake (increase energy) SARI-Serotonin Antagonist Reuptake Inhibitors
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Question:
Selective Serotonin Reuptake Inhibitors (SSRIs): Most adverse effects will
subside after 4-5 days once the body adjusts to increased serotonin levels.
Answer:
diarrhea headache weight gain sexual side effects
Question:
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs): Medications should
not be abruptly stopped to avoid discontinuation symptoms. NE effects of the medication may increase anxiety in some clients. Report worsening anxiety to the provider.
Answer:
elevated blood pressure anxiety insomnia constipation
Question:
Norepinephrine Dopamine Reuptake Inhibitors (NDRI): Take medication in
the morning. Stop taking medication if seizures occur. Stop taking medication if anxiety is noted. 2 / 4
Answer:
agitation headache dry mouth constipation weight loss
Question:
escitalopram (Lexapro) SSRI
Answer:
no known drug interactions best tolerated SSRI 27-32 hour half-life good for forgetful prone clients least CYP reactions Substrate for 3A4
Question:
citalopram (Celexa) SSRI
Answer:
mild antihistamine effects; Half-Life: 23-45 hours
Weak Inhibitor of 2D6
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Question:
fluoxetine (Prozac) SSRI
Answer:
longest half-life Use caution in patients with comorbid anxiety due to risk for activation and panic attacks
Half-Life: 2-3 days parent, 2 week metabolite
Inhibits 2D6 and 3A4
Question:
paroxetine (Paxil) SSRI
Answer:
also treats social anxiety and insomnia associated with weight gain will experience withdrawal with missed dose or abrupt stop
Half-Life: 24 hours
Inhibits 2D6
Question:
fluvoxamine (Luvox) SSRI
Answer:
treats anxious depression smokers require an increased dose
Half-Life: 9-28 hours
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