Final Exam: NR565 NR 565 Advanced

Final Exam: NR565/ NR 565 Advanced

Pharmacology Care of the Fundamentals Exam | Questions and Verified Answers (2023/ 2024 Update)- Chamberlain In which patient population is Metformin contraindicated in?

• Diabetics with HA1c < 7.0%
• Patients older than 50
• Alcoholics
• Women suffering from infertility - ANSWER C. Alcoholics

What lab value suggests metformin might be contraindicated?

• eGFR <30
• Crea 0.8

C. WBC 7.8

• Bun 17 - ANSWER A. eGFR <30

What medication is contraindicated to treat diabetes if a patient already has a cardiac ejection fraction rate of 40%?

• Second Generation sulfonyureas
• Thiazolidinediones
• Dopamine Agonist
• Glucosidase Inhibitor - ANSWER B. Thiazolidinediones 1 / 3

Sabrina is a 35-year-old female who presents with complaints of fatigue, anxiety, and palpitations. She has a long history of obesity and reports that she is happy that she has lost 23 pounds in the last 2 months. She also reports that she has trouble sleeping and her husband complains that she is keeping the house too cold.Physical exam reveals slight tachycardia at 104 bpm and a slightly enlarged thyroid. Thyroid testing reveals hyperthyroidism or Grave's disease.Which of the following agents is the first-line treatment for hyperthyroidism or Grave's disease?

• Methimazole
• Metoprolol
• Allopurinol
• Levothyroxine - ANSWER A. Methimazole

Which of the following medications would be considered the first line of treatment for a newly diagnosed Diabetic patient with adequate renal and hepatic function?

A: NovoLog Sliding Scale Insulin

B: Liraglutide (Victoza)

C: Oral Metformin

D: Glipizide - ANSWER C: Oral Metformin Of the following medications, which is most likely to cause hypoglycemia?

• Metformin
• Insulin
• Incretin mimetics
• Thiazolidinediones - ANSWER B. Insulin

Which symptoms are most expected of a patient diagnosed with hypothyroidism?

• shortness of breath, wheezing, fatigue
• tachycardia, insomnia, weight loss, goiter 2 / 3

• irritability, anxiety, dizziness, increased sweating
• dry pale skin, brittle hair, fatigue, myxedema - ANSWER D. dry

skin, brittle hair, fatigue, myxedema Patients with an increased risk for UTIs and genital infections or an active diagnosis, should avoid what drug class/es for treatment of Type II Diabetes?

• Thiazolidinediones (Glitazones)
• Biguanide.
• Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors.
• All of the above. - ANSWER C. Sodium-Glucose Cotransporter
• (SGLT-2) Inhibitors.

A 45-year-old patient with a history of type 2 diabetes presents to the clinic for a follow-up appointment. The healthcare provider has prescribed metformin as part of the treatment plan. Which of the following statements regarding metformin is correct?

• Metformin primarily stimulates insulin production from the pancreas.
• Metformin reduces glucose levels primarily by decreasing insulin resistance.
• Metformin is associated with a risk of hypoglycemia.
• Metformin improves insulin sensitivity and reduces hepatic glucose production.
• ANSWER D. Metformin improves insulin sensitivity and reduces

hepatic glucose production.In what part of the body are SGLT-2 (sodium-glucose cotransporter 2) inhibitors active?

• Small intestine
• Pancreas
• Renal tubules
• Stomach - ANSWER C. Renal tubules
• / 3