NR-565 Advanced Pharmacology Fundamentals
Final Exam Study Guide
Who can receive preventative therapy for migraines?
Correct Answer:
- or more severe headaches per month that do not respond to abortive
therapy.
opioid analgesics for severe migraines that don't respond to first-line medications
Correct Answer:
butorphanol nasal spray
MOA triptans
Correct Answer:
selective activation of 5-HT1B and 5- HT1D receptors
Contraindications for triptans
Correct Answer:
acute ischemic heart disease, MI, uncontrolled hypertension
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Rivastigmine Patient teaching
Correct Answer:
Falls are common so instruct patient and family on fall precautions for use in the home. If dizziness of lightheadedness occurs get up slowly or lie down until it passes. Encouraged supplemental meals and snacks to encourage optimal weight. Keep a list of new problems and concerns to be discussed at appointment.
When to increase dose of donepezil
Correct Answer:
after 1-3 months to reduce side effects
Side effects of cholinesterase inhibitors
Correct Answer:
nausea, vomiting, dyspepsia, diarrhea, dizziness, headache, bronchoconstriction, USE CAUTIOUSLY IN PATIEN TS WITH COPD, bradycardia, fainting, falling, fractures.
Most common adverse effect Pramipexole
Correct Answer:
Nausea, dizziness, daytime somnolence, insomnia, constipation, weakness, and hallucinations. Sleep attacks. Overwhelming and irresistible sleepiness.
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when is pramipexole best used in treating PD?
Correct Answer:
Used alone in early stages of PD and combined with levodopa in advanced stages.
When to use/prescribe COMT inhibitors
Correct Answer:
add to levodopa/carbidopa to increase levodopa concentrations, extend half- life, and decrease wearing off time.
How to manage side effects of bromocriptine?
Correct Answer:
reduce the dose
common side effects of phenytoin
Correct Answer:
Nystagmus, gingival hyperplasia, morbilliform, DRESS, when given IV cardiac dysrhythmias and hypotension. NO PREGNANCY. Hirsutism, rickets, osteomalacia
Which anticonvulsant would be given for someone with epilepsy needing adjunctive therapy for partial seizures with or without secondary generalization?
Correct Answer:
Gabapentin
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