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HESI Case Study: Depression
Questions and Answers | Latest Version | 2025/2026 | Correct & Verified
What is the primary neurotransmitter often linked to depression?✔✔Serotonin
Which type of therapy focuses on changing negative thought patterns in depression?✔✔Cognitive behavioral therapy
What is the most common symptom reported by patients with major depressive disorder?✔✔Persistent sadness
Which screening tool is commonly used to assess depression severity?✔✔PHQ-9 (Patient Health Questionnaire-9)
What sleep disturbance is most often associated with depression?✔✔Early morning awakening
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What is the priority nursing action when a patient expresses suicidal thoughts?✔✔Ensure safety and initiate suicide precautions
Which medical condition can mimic symptoms of depression?✔✔Hypothyroidism
What is the therapeutic effect of SSRIs in depression?✔✔Increase serotonin availability at synapses
Which gender is statistically at higher risk for developing depression?✔✔Women
What is the first-line pharmacological treatment for major depressive disorder?✔✔Selective serotonin reuptake inhibitors (SSRIs)
Which age group is most vulnerable to untreated depression leading to suicide?✔✔Adolescents and older adults
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What is the most reliable indicator of suicide risk in a depressed patient?✔✔Previous suicide attempt
Which cognitive symptom is common in depression?✔✔Difficulty concentrating
What physical symptom often accompanies depression?✔✔Changes in appetite or weight
Which lab test should be ruled out before diagnosing depression?✔✔Thyroid function test
What is the nurse’s best response when a depressed client says, “I feel worthless”?✔✔Acknowledge feelings and encourage expression
What type of depression occurs only during certain seasons?✔✔Seasonal affective disorder
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