HESI Case Study - Pernicious Anemia

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HESI Case Study - Pernicious Anemia Questions and Answers | Latest Version | 2025/2026 | Correct & Verified

Which vitamin deficiency causes pernicious anemia?

• Vitamin C
• Vitamin D

✔✔C. Vitamin B12

• Vitamin K

Which substance is lacking in the stomach of patients with pernicious anemia?

• Pepsin
• Hydrochloric acid

✔✔C. Intrinsic factor

• Amylase

Which type of anemia is caused by pernicious anemia?

• Microcytic

✔✔B. Macrocytic 1 / 4

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• Hemolytic
• Normocytic

Which neurological symptom is common in pernicious anemia?

• Muscle twitching

✔✔B. Numbness and tingling in extremities

• Seizures
• Facial droop

Which diagnostic test confirms pernicious anemia?

• Chest x-ray

✔✔B. Schilling test

C. EEG

D. ECG

Which tongue appearance is typical in pernicious anemia?

• Coated and white
• Pale and moist 2 / 4

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✔✔C. Red and smooth (glossitis)

• Thick and fissured

Which population is at higher risk for pernicious anemia?

• Children

✔✔B. Older adults

• Teenagers
• Newborns

Which injection is the standard treatment for pernicious anemia?

• Iron

✔✔B. Vitamin B12

• Folic acid
• Vitamin C

What is the route of administration for long-term vitamin B12 therapy in pernicious anemia?

• Oral

✔✔B. Intramuscular 3 / 4

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• Subcutaneous
• Inhaled

Which lab finding supports pernicious anemia?

• Low mean corpuscular volume (MCV)

✔✔B. High mean corpuscular volume (MCV)

• High white blood cell count
• Low platelet count

Which symptom indicates severe pernicious anemia?

• Headache
• Mild fatigue

✔✔C. Difficulty walking due to nerve damage

• Itchy skin

Which type of cells appear in a blood smear of pernicious anemia?

• Small red cells

✔✔B. Large oval red cells (macro-ovalocytes)

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