HESI Comprehensive Questions and

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HESI Comprehensive Questions and Answers | Latest Version | 2025/2026 | Correct & Verified

A client with pneumonia is receiving IV antibiotics. Which finding indicates the treatment is effective?

• Temperature 101°F
• White blood cell count 15,000

✔✔C. Clear breath sounds and improved oxygen saturation

• Productive cough with yellow sputum

A client is prescribed warfarin. Which instruction is most important?

• Take medication with milk
• Limit intake of citrus fruits

✔✔C. Report unusual bruising or bleeding immediately

• Expect frequent headaches as a side effect

A client with COPD is prescribed oxygen at 2 L/min via nasal cannula. Why is this rate important? 1 / 4

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• It improves lung compliance

✔✔B. Higher oxygen can suppress respiratory drive

• It prevents atelectasis
• It reduces bronchospasms

A nurse is assessing a client receiving digoxin. Which finding requires immediate action?

• Heart rate 72/min

✔✔B. Heart rate 48/min

• Blood pressure 130/70 mmHg
• Respiratory rate 20/min

A client with diabetes reports blurry vision and frequent urination. Which complication is most likely?

• Hypoglycemia

✔✔B. Hyperglycemia

• Hyponatremia
• Hypocalcemia
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A client is scheduled for surgery and says, “I’m afraid I won’t wake up.” Which nursing response is best?

• “Don’t worry, everything will be fine.”
• “Why would you think that way?”

✔✔C. “It sounds like you are feeling anxious. Tell me more about your fears.”

• “Many people feel scared before surgery.”

A postpartum client with a firm fundus reports heavy bleeding. What is the priority action?

• Administer IV fluids

✔✔B. Assess for bladder distension

• Call the provider immediately
• Increase oxytocin infusion

A client with heart failure is prescribed furosemide. Which dietary teaching is correct?

• Avoid bananas
• Eat more processed foods

✔✔C. Increase potassium-rich foods

• Restrict protein intake 3 / 4

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A nurse is teaching a client prescribed sertraline for depression. Which statement indicates understanding?

• “I can stop this medication once I feel better.”

✔✔B. “It may take a few weeks before I notice improvement.”

• “This medication will make me sleepy all the time.”
• “I can drink alcohol with this medication.”

A client is receiving blood transfusion and develops fever and chills. What is the nurse’s first action?✔✔A. Stop the transfusion immediately

• Document the reaction
• Administer acetaminophen
• Notify the blood bank

A client with cirrhosis has ascites and shortness of breath. Which intervention is most important?

• Encourage ambulation

✔✔B. Place the client in high Fowler’s position

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