HESI CS Schizophrenia Questions and

1

HESI CS – Schizophrenia Questions and Answers | Latest Version | 2025/2026 | Correct & Verified

Which symptom is considered a positive symptom of schizophrenia?

• Lack of motivation

✔✔B. Auditory hallucinations

• Flat affect
• Social withdrawal

Which neurotransmitter is most associated with schizophrenia?

• Serotonin

✔✔B. Dopamine

• Norepinephrine
• Acetylcholine

Which type of delusion involves the belief that others are plotting harm?

• Grandiose delusion

✔✔B. Persecutory delusion 1 / 4

2

• Somatic delusion
• Nihilistic delusion

Which nursing action is most appropriate when a patient is experiencing hallucinations?

• Argue with the hallucination

✔✔B. Acknowledge the patient’s experience without validating it

• Ignore the patient’s statements
• Encourage the hallucination

Which medication class is first-line for schizophrenia?

• Antidepressants
• Benzodiazepines

✔✔C. Antipsychotics

• Anticonvulsants

Which antipsychotic medication has the highest risk of agranulocytosis?

• Risperidone
• Haloperidol 2 / 4

3

✔✔C. Clozapine

• Olanzapine

Which side effect is associated with long-term use of antipsychotics?

• Hypoglycemia

✔✔B. Tardive dyskinesia

• Hypertension
• Kidney failure

Which symptom reflects disorganized thinking in schizophrenia?

• Sleep disturbance

✔✔B. Loose associations

• Lack of hygiene
• Weight gain

Which term describes a lack of emotional expression?

• Flight of ideas
• Word salad 3 / 4

4

✔✔C. Flat affect

• Delusion

Which priority need is essential for a patient with schizophrenia experiencing paranoia?

• Increased activity

✔✔B. Establishing trust and safety

• Group therapy
• Spiritual counseling

Which lab test is required before starting clozapine therapy?

• Liver function test

✔✔B. White blood cell count

• Kidney function test
• Lipid panel

Which intervention helps reduce social isolation in schizophrenia patients?

• Encourage watching TV alone
• Suggest self-study activities
• / 4