HESI Pharmacology Exam Version 5 | 55 Questions and Verified Answers
| 2024 / 2025
Question 1:
A client is to begin a 6-month course of therapy with isoniazid (INH). A nurse
plans to teach the client to:
Answer:
Report yellow eyes or skin immediately.
Rationale: INH is hepatotoxic, and therefore the client is taught to report
signs and symptoms of hepatitis immediately (which include yellow skin and sclera). For the same reason, alcohol should be avoided during therapy. The client should avoid intake of Swiss cheese, fish such as tuna, and foods containing tyramine because they may cause a reaction characterized by redness and itching of the skin, flushing, sweating, tachycardia, headache, or lightheadedness.
Question 2:
A client has been started on long-term therapy with rifampin (Rifadin). A
nurse teaches the client that the medication:
Answer:
Causes orange discoloration of sweat, tears, urine, and feces 1 / 4
Rifampin should be taken exactly as directed. Doses should not be doubled or skipped. The client should not stop therapy until directed to do so by a health care provider. The medication should be administered on an empty stomach unless it causes gastrointestinal upset, and then it may be taken with food.Antacids, if prescribed, should be taken at least 1 hour before the medication.Rifampin causes orange-red discoloration of body secretions and will permanently stain soft contact lenses.
rifampin (Rifadin) It can treat tuberculosis (TB) when used along with other medications.
Question 3:
A nurse has given a client taking ethambutol (Myambutol) information about the medication. The nurse determines that the client understands the
instructions if the client states that he or she will immediately report:
Answer:
Problems with visual acuity
Ethambutol causes optic neuritis, which decreases visual acuity and the ability to discriminate between the colors red and green. This poses a potential safety hazard when a client is driving a motor vehicle. The client is taught to report this symptom immediately. The client is also taught to take the medication with food if GI upset occurs. Impaired hearing results from antitubercular therapy with streptomycin. Orange-red discoloration of secretions occurs with rifampin (Rifadin)
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Ethambutol - Ethambutol eliminates certain bacteria that cause tuberculosis (TB). It is used with other medicines to treat tuberculosis and to prevent you from giving the infection to others.
Question 4:
Cycloserine (Seromycin) is added to the medication regimen for a client with tuberculosis. Which of the following would the nurse include in the client- teaching plan regarding this medication?
Answer:
To return to the clinic weekly for serum drug-level testing
Cycloserine (Seromycin) is an antitubercular medication that requires weekly serum drug level determinations to monitor for the potential of neurotoxicity.Serum drug levels lower than 30 mcg/mL reduce the incidence of neurotoxicity. The medication must be taken after meals to prevent gastrointestinal irritation. The client must be instructed to notify the HCP if a skin rash or signs of central nervous system toxicity are noted. Alcohol must be avoided because it increases the risk of seizure activity.
Cycloserine (Seromycin) - Treating tuberculosis (TB) in the lungs and other places in the body (including the kidneys) when treatment with other medicines has not been effective. Cycloserine should be used in combination with other medicines. It may also be used to treat certain urinary tract infections.
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Question 5:
A client with tuberculosis is being started on antituberculosis therapy with isoniazid (INH). Before giving the client the first dose, a nurse ensures that which of the following baseline studies has been completed?
Answer:
Liver enzyme levels
INH therapy can cause an elevation of hepatic enzyme levels and hepatitis.Therefore, liver enzyme levels are monitored when therapy is initiated and during the first 3 months of therapy. They may be monitored longer in the client who is greater than age 50 or abuses alcohol.
Question 6:
Rifabutin (Mycobutin) is prescribed for a client with active Mycobacterium avium complex (MAC) disease and tuberculosis. The nurse monitors for which side effects of the medication? Select all that apply.
Answer:
Signs of hepatitis Flu-like syndrome Low neutrophil count Ocular pain or blurred vision
Rifabutin (Mycobutin) may be prescribed for a client with active MAC disease and tuberculosis. It inhibits mycobacterial DNA-dependent RNA polymerase and suppresses protein synthesis. Side effects include rash, gastrointestinal disturbances, neutropenia (low neutrophil count), red-orange body secretions, uveitis (blurred vision and eye pain), myositis, arthralgia,
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