HESI RN Exit Exam Sample Study Guide with

HESI RN Exit Exam Sample Study Guide with 80 Questions 2025/2026 Contents

• Introduction3
• Multiple-Choice Questions3

2.1 Priority Questions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.2 Pharmacology Questions . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.3 Medical-Surgical Questions . . . . . . . . . . . . . . . . . . . . . . . . . 5 2.4 Pediatric Questions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 2.5 Maternity Questions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7

• Select-All-That-Apply Questions8

3.1 Infection Control . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 3.2 Pharmacology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9

• NGN-Style Case Study Questions11

4.1 Case Study 1: Postpartum Care . . . . . . . . . . . . . . . . . . . . . . . 11 4.2 Case Study 2: Pediatric Asthma . . . . . . . . . . . . . . . . . . . . . . . 12 4.3 Case Study 3: Myocardial Infarction . . . . . . . . . . . . . . . . . . . . 13

• Dosage Calculation Questions14

5.1 Fill-in-the-Blank . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 5.2 Calculation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14

• Hot Spot Questions15

6.1 Assessment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15

• Psychiatric Nursing Questions15
• Additional Questions16

8.1 Medical-Surgical . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 8.2 Pediatric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 8.3 Maternity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 8.4 Psychiatric Nursing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 8.5 Additional Calculations . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 8.6 Additional Hot Spot . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 8.7 Additional NGN Case Study . . . . . . . . . . . . . . . . . . . . . . . . . 20

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• Study Tips21

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• Introduction

This study guide provides 80 practice questions designed to mimic the HESI RN Exit Exam, assessing readiness for the NCLEX-RN. Questions cover nursing pro- cess, client needs, pharmacology, medical-surgical, pediatrics, maternity, psy- chiatric nursing, and Next Generation NCLEX (NGN)-style case studies. Each question includes a detailed rationale to enhance understanding.

• Multiple-Choice Questions

2.1 Priority Questions

Question 1:A client with heart failure develops dyspnea, crackles, and a heart

rate of 110 bpm. What is the priority action?

• Administer oxygen at 2 L/min via nasal cannula
• Elevate the head of the bed to 45 degrees
• Notify the healthcare provider
• Check the client’s blood pressure

Answer:A

Rationale:Symptoms suggest acute pulmonary edema. Administering oxygen

(A) is the priority per ABCs (Airway, Breathing, Circulation).

Question 2:A client with chest pain shows ST elevation on ECG. What is the pri-

ority?

• Administer aspirin
• Prepare for thrombolytic therapy
• Obtain another ECG
• Apply oxygen at 4 L/min

Answer:D

Rationale:Oxygen (D) reduces myocardial oxygen demand in a possible my-

ocardial infarction.

Question 3:A client with a head injury has unequal pupils and decreasing con-

sciousness. What is the priority?

• Administer mannitol
• Elevate the head of the bed
• Notify the neurologist
• Check blood glucose
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