Kee.Marshall Test Bank

NUR Clinical Calculations 9th Edition Kee.Marshall Test Bank

Chapter 07: Methods of Calculation for Individualized Drug Dosing

Kee: Clinical Calculations: With Applications to General and Specialty Areas, 9th Edition

OTHER

Body Surface Area by Square Root

1. Order: cyclophosphamide 500 mg/m

2 in 500 mL of normal saline solution (NSS) over 90 minutes

Patient height and weight: 5 ft 10 in, 142 lb

Drug available: cyclophosphamide 100 mg dilute with 5 mL of sterile water; yields 20 mg/mL

• What is the patient’s body surface area (BSA) (m

2 )?

• What is the total dose?
• How many milliliters should you prepare?

ANS:

a.

• 500 mg/m

2  1.78 m 2 = 890 mg

c. FE: 890 mg/100 mg  5 mL = 44.5 mL

OR

2. Order: cisplatin 50 mg/m

2 in 500 mL of NSS intravenously over 90 minutes

Patient height and weight: 5 ft 6 in, 160 lb

Drug available: cisplatin 100 mg/100 mL

• What is the patient’s BSA (m

2 )?

• What is the total dose?
• How many milliliters should you prepare?

ANS:

a.

• 50 mg  1.84 m

2 = 92 mg

c. FE: 92 mg/100 mg  100 mL = 92 mL

OR

• For the following questions, use the square root method and/or nomogram. Note discrepancies

between methods. 1 / 4

• For the following questions, use the square root method and/or nomogram. Note discrepancies

between methods.

Give dacarbazine 250 mg/m 2 /day  5 days.

Patient height: 5 ft 10 in

Patient weight: 173 lb

What is the daily dose with

• square root method?
• nomogram?

ANS:

a.250 mg/m 2 /day  1.97 m 2 = 493 mg/day

• Height 70 in, weight 173 lb, intersects 2.02 m

2

250 mg/m 2 /day  2.02 m 2 = 505  500 mg/day 2 / 4

• For the following questions, use the square root method and/or nomogram. Note discrepancies

between methods.

Give 5-fluorouracil 450 mg/m 2 /wk.

Patient height: 5 ft 6 in

Patient weight: 210 lb

What is the weekly dose with

• square root method?
• nomogram?

ANS:

a.450 mg/m 2 /wk  2.10 m 2 = 945 mg/wk

• Height 66 in, weight 210 lb, intersects 2.04 m

2

450 mg/m 2 /wk  2.04 m 2 = 918  920 mg/wk 3 / 4

Give leucovorin 200 mg/m 2 /wk.

Patient height: 5 ft 6 in

Patient weight: 210 lb

What is the weekly dose with

• square root method?
• nomogram?

ANS:

a.200 mg/m 2 /wk  2.10 m 2 = 420 mg/wk

• Height 66 in, weight 210 lb, intersects 2.04 m

2

200 mg/m 2 /wk  2.04 m 2 = 408.00  400 mg/wk

• For the following questions, use the square root method and/or nomogram. Note discrepancies

between methods.

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