LAT 347 Study Questions with Correct Answers 2023/2024 Verified Answers When developing a new drug what is the correct order of testing? - Correct Answer In Vitro preclinical and clinical How often does the animal welfare regulations require the IACUC to review and do inspections of the facilities? - Correct Answer At least every six months Which of the agencies regulates disinfectants and sterilizers used on hard surfaces? - Correct Answer United States and environmental protection Agency What type of floor plan is designed so each room has exit doors to a Dirty corridor that wraps around the periphery of the floor plan? - Correct Answer Three-corridor What is a biofilm? - Correct Answer Microrganism build-up on tank wall What substance can be added to an aquatic system to raise pH? - Correct Answer Sodium bicarbonate Which parameter is a measure of both calcium and magnesium ions in water? - Correct Answer Total hardness AWR (enforced by USDA) require IACUC have how many members? - Correct Answer A tleast 3.Chairperson,vet,and a member not associated with inst.PHS policy requires how many IACUC members? - Correct Answer At least 5.Chairperson,vet,scientist,nonscientist, and community member.Nonfederal research facilities must register with USDA if species are covered by? - Correct Answer AWA.Updates every 3 yrs. signed by IO. 1 / 3
Inst. housing USDA Covered animals must submit a report how often to the USDA? - Correct Answer Annually (PHS) Public health service - Correct Answer Publishes the policy on the humane care and use of laboratory animals.
(AAALAC)
Association for Assessment and Accreditation of Laboratory Animal Care International - Correct Answer Provides peer evaluation of animal care and use programs (AWR) Animal welfare regulation - Correct Answer Describes what a facility must do to comply with the AWA (FDA) Food and drug administration - Correct Answer Requires compliance with the good laboratory practices (GLPs)
(USDA)
U.S. Department of agriculture - Correct Answer Registers institutions using species covered by animal welfare act What two federal agencies require compliance with the GLPs? - Correct Answer (EPA)environmental protection agency and (FDA) food and drug admin.How often must insitutions update registration with USDA if using AWA species? - Correct Answer Every
- yrs
What agency enforces the PHS policy? - Correct Answer (OLAW) Office of laboratory animal welfare 2 / 3
What document is signed by IO and is filed to commit the institution to compliance with the PHS policy?
- Correct Answer Animal welfare assurance
- / 3
What animals are covered under the PHS policy? - Correct Answer ALL vertebrates USDA covered animals submit a report to the USDA how often? - Correct Answer Annually USDA covered species may only be approved for how long? - Correct Answer 1 year USDA vet med officers (VMO) conduct unannouced ispections how often? - Correct Answer Atleast annually IACUCs are mandated by what? - Correct Answer Federal mandate What is a quality assurance unit responsible for ensuring compliance with? - Correct Answer GLP Which organization uses the GUIDE as one of its standards for accreditation of Lab animal programs? - Correct Answer AAALAC Most aquatic tanks are made of what plastic? - Correct Answer Polycarbonate and polysulfone Water conductivity is? - Correct Answer Measure of amount of dissolved salts and minerals Water hardness is the measure of what? - Correct Answer Specific ions dissolved in the water What two ions are main ones measured by hardness? - Correct Answer Calcium and magnesium What percentage of oxygen by volume is in water? - Correct Answer Less than 1%