BIOD322 / BIOD 322 Module 8 (Latest Update 2025 / 2026) Neuroscience | Questions & Answers | Grade A | 100% Correct - Portage Learning
Diseases of the Nervous System
Question:
What is a diathesis?
Answer:
Predisposition for a disease
Question:
What hypothesis states that affective disorders is based on the observation that mood disorders have a tendency to be more common in families with common genetics
Answer:
Diathesis-stress hypothesis
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Question:
In the diathesis-stress hypothesis, what is the axis where both genetic and environmental factors converge to influence mood disorders?
Answer:
Hypothalamic pituitary axis (HPA)
Question:
HPA axis seems to be hyperactive in depressive individuals, oversecreting what 3 substances?
Answer:
- Corticotropin-releasing factor (CRF)
- Adrenocorticotropic hormone (ACTH)
- Cortisol
Question:
Therapist-guided form of talk therapy that may help a person manage their depression
Answer:
Cognitive behavioral therapy
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Question:
Four treatment classes for MDD
Answer:
- Cognitive Behavior Therapy
- Pharm treatments
- Electroconvulsive therapy
- Deep brain stimulation
Question:
What are the three classes of anti-depressant (Pharmacological) drugs developed to treat MDD?
Answer:
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants (TCAs)
- Selective serotonin reuptake inhibitors (SSRIs) + SNRIs
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Question:
The first anti-depressant drugs acted to increase the action of what type of neurotransmitters? Which neurotransmitters? (3)
Answer:
Monoamine neurotransmitters
Dopamine, norepinephrine, and serotonin
Question:
What enzyme degrades the monoamine neurotransmitters into inactive components that don't signal to receptors at the synapse?
Answer:
Monoamine oxidase (MAO)
Question:
The first generation of antidepressants blocked MAO. What are they called and what is the mechanism in brief
Answer:
Monoamine oxidase inhibitors (MAOIs) Neurotransmitter will remain in the synapse longer
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