1 .dopaminergic agent levodopa/carbidopa 2 .anticholinergic agent benzotrophine 3 .cholinesterase inhibitor donepezil 4 .Immunomodula- tors interferon beta 5 .traditional anti epileptic drugs phenytoin, carbamazepine, valproic acid 6 .atypical anti epileptic drugs oxcarbazepine lamotrigdine 7 .barbituratesPhenobarbital 8 .muscle spams drugs baclofen dantrolene 9 .1st generation antipsychotics
low potency: chlorpromazine
high potency: haloperidol
10 .2nd generation antipsychotic clozapine risperdoneolanzapine 11 .SSRIs fluoxetine sertralineparoxetine 12 .SNRI venlafaxine duloxetine 13 .TCA amitriptyline 14 .MAOI phenelzine
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NUR 2474 Rasmussen Pharmacology Exam 1 1 / 3
15 .atypical antide- pressant Bupropion, trazodone 16 .OTC herbal for depression ST. Johns Wort 17 .mood stabilizerlithium 18 .benzodiazepineslorazepam, diazepam alprazolam 19 .benzodiazepine like drugs zolpidem 20 .insomnia drugs used trazodone doxepin 21 .OTC drug for in- somnia melatonin 22 .Atypical Anxi- olytic Buspirone 23 .amphetaminesamphetamine, lisdexamfetaminemethamphetamine 24 .methylxanthinesmethylphenidate 25 .when should we complete blood testing with use of lithium?early in therapy- every 2-3 days, until a therapeutic dose has been established, then long term-every 3 to 6 months 26 .therapeutic level of lithium
0.8-1.4
mEq/L 27 .toxic level of lithium greater than 1.5 mEq/L
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28 .when can we start to see side effects of lithi-um?when the drug is at a therapeutic level. they are expected.29 .what are the side effects of lithium (therapeutic lev-el)?GI effects, tremors, polyuria, renal toxicity, goiter, hypothy- roidism, teratogenesis.30 .what will hap- pen to side ef-fects when one has a toxic level of lithium?the effects will be much worse and possibly life threaten- ing i.e. tremor that becomes larger with muscle incoordi-nation 31 .what medica- tions can we use to treat the cyclic effects of bipo-lar (mood-de-pression- psy-chosis)?mood stabilizer (lithium)= control mood antidepressant (SSRI,TCA,MAOI)= control depressionantipsychotic (Ist/2nd generation)= control the psychosis 32 .how does a ben- zodiazepine help with ETOH with-drawal?it will decrease the withdrawal manifestations and intensi- ty, while making one sleepy and having CNS depression. plus, it is easy to give IM and will work quickly.33 .what is a pop- ular benzodi-azepine that is used to treat anx-iety?alprazolam (think A-anxiety) 34 .how does alpra- zolam work to re-duce anxiety?it inhibits GABA in the CNS, depressing the CNS.35 .
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