Medical Microbiology 8th Edition Murray Test Bank

Medical Microbiology 8th Edition Murray Test Bank

Murray: Medical Microbiology, 8th Edition

Chapter 5: Molecular Diagnosis

Test Bank

MULTIPLE CHOICE

• Target nucleic acid amplification (PCR) methods are based on which of the

following?

• The ability of two nucleic acid strands that have complementary base sequences to

specifically bond with each other and form a double-stranded molecule

• Detecting phenotypic traits not detectable by conventional strategies
• The principles of complementary nucleic-acid hybridization and those of nucleic-

acid replication that are applied repeatedly through numerous cycles

• Determining the exact nucleotide sequence of a gene or gene fragment obtained

from an organism

ANS: C

• A reduction in production of HIV due to therapy can be evaluated by which of the

following methods?

• ELISA assay for antibody of pN

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• Western blot for antibody of patient serum
• PCR analysis of patient serum
• Real-time PCR of patient serum
• Immunofluorescence of peripheral blood T cells

ANS: D

• A 27-year-old man has focal neurologic symptoms, and MRI indicates inflammation

in the temporal lobe. Which test would be most effective to confirm the diagnosis?

• ELISA assay for antibocy of patient serum
• Western blot for antibody of patient serum
• PCR analysis of patient serum
• Real-time PCR of patient serum
• Immunofluorescence of peripheral blood T cells

ANS: C 1 / 4

Murray: Medical Microbiology, 8th Edition

Chapter 6: Serologic Diagnosis

Test Bank

MULTIPLE CHOICE

• A 22-year-old spelunker has flulike illness with chest pain. Radiographs of the lungs

indicate patchy infiltrates. Which of the following serologic findings would confirm a diagnosis of histoplasmosis?

• Ouchterlony demonstration of partial identity with Blastomyces
• A twofold increase in complement fixation titer
• Inhibition of hemagglutination
• Real-time PCR
• Southern blot analysis of serum

ANS: A

• A 33-year-old man is suspected of being infected with H3N2 influenza. Comparison of

serum taken during disease is compared to serum taken 2 months after recovery. Which of the following sets of antibody titers would confirm infection with the H3N2 strain?valescent N TU iteR rSINGTB.COM

ANS: B

• Serology is used to follow the course of which of the following diseases?
• Influenza
• Herpes simplex virus
• Epstein Barr virus
• Yellow fever virus
• Measles

ANS: C

• Serum levels of which antibody is indicative of recent infection?
• IgA
• IgD
• IgE
• IgG

Acute Titer Con

• 8 16
• 8 64
• 4 8
• 16 8
• 64 16
• / 4

Test Bank 6-2

• IgM

ANS: A

• / 4

Murray: Medical Microbiology, 8th Edition

Chapter 7: Elements of Host Protective Responses

Test Bank

MULTIPLE CHOICE

• How can a B cell be distinguished from a T cell?
• B cells have a large nucleus-to-cytoplasm ratio.
• B cells have surface immunoglobulin.
• T cells mature in the bone marrow.
• Extensive gene recombinations occur in B cells.
• B cells have a sheep red-blood-cell receptor.

ANS: B

• Which cell type would not be present in a boy born without a thymus?
• NK cell
• B cell
• T cell
• Macrophages
• Neutrophils

ANS: C

• Which cell type produces acute-phase cytokines?
• B cell
• T cell
• NK cell
• Macrophages
• Neutrophils

ANS: D

• A ruptured spleen was removed from a 37-year-old car accident victim. What would be

the consequence?

• Can’t mature T cells
• Lack of IgG-producing B cells
• Lack of IgA-producing B cells
• Can’t activate macrophages
• Increased susceptibility to encapsulated bacteria

ANS: E

• / 4