Midterm Exam: NR565 NR 565

Midterm Exam: NR565/ NR 565

Advanced Pharmacology Care of the Fundamentals Exam | Questions and Verified Answers ( 2025/ 2026 Update)- Chamberlain When prescribing Medications, we must understand that the liver function declines with age d/t what?

• Enlarged Liver
• Decreased blood flow to liver
• Increased activity of the hepatic enzymes - ANSWER B.

Decreased blood flow to liver An 82 yo male visits the clinic complaining that his pain meds "take forever" to work after he takes his pill. What are possible reasons you can explain to him as to why this may be happening.

• Perhaps we need to increase your dose
• Sometimes as you get older, absorption may be slower resulting in a delayed

response

• As we get older, the gastric acid decreases and may delay absorption -

ANSWER B. Sometimes as you get older, absorption may be slower resulting in a delayed response

• As we get older, the gastric acid decreases and may delay absorption

RA Characteristics 1 / 3

Onset Affected population Location Joint stiffness duration SxS - ANSWER weeks-months women>men common hands, feet, & wrists >60 min in AM local & sys.OA Characteristics Onset Affected population Location Joint stiffness duration SxS - ANSWER years men & Women equally Hands & weight baring joints <30min in AM typically local What might you expect to find in the synovial fluid of a pt with OA - ANSWER Mild leukocytes What might you expect to find in the synovial fluid of a pt with RA - ANSWER Cloudy with leukocytes 2 / 3

Goals of Tx for RA - ANSWER Sxs relief (pain, stiffness, inflammation, maintaining joint fxn and ROM minimize systemic involvement delay progression Typical pharm Txs for RA - ANSWER NSAIDs, systemic steroids, antimalarials, antimetabolites, and biologics Baseline assessment data before starting DMARD - ANSWER Liver, PG, serum creatinine, CBC with diff, sxs of infxn (TB & hepatits), Hx & physical, renal status, & malignancies Significant baseline data for Sulfasalazine - ANSWER CXR, pulmonary and neuro status Significant baseline data for Leflunomide - ANSWER CXR, BP & pulmonary status

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