NR-565 Advanced Pharmacology Fundamentals
Midterm Exam Q & A Study Set
Pharmacokinetics
Correct Answer:
The process by which drugs are absorbed, distributed within the body, metabolized, and excreted.
Pharmacodynamics
Correct Answer:
The study of what the drug does to the body
Cytochrome P450 (CYP450)
Correct Answer:
xenobiotic-metabolizing enzymes necessary for the production of cholesterol and steroids and the detoxification of chemicals and drug metabolism.
Function of Cytochrome P450 (CYP450)
Correct Answer:
responsible for phase 1 metabolism in which drugs are oxidized, reduced, or hydrolyzed
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Three possible outcomes of phase 1 drug metabolism.
Correct Answer:
-Drug becomes completely inactive
-Drug becomes partially inactive but one or more metabolites remain active
-Original drug is not pharmacologically active but one metabolite remains active
CRAP GPS induces my rage
Correct Answer:
CRAP GPS
Carbamazepine Rifampin Alcohol Phenytoin Griseofulvin Phenobarbital Sulfonylureas
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VISA CK GQ
Correct Answer:
VISA CK GQ
Valproate Isoniazid Sulfonamides Amiodarone Chloramphenicol Ketoconazole Grapefruit Juice Quinidine
Beers Criteria
Correct Answer:
-potentially Inappropriate Medication (PIM) use in older adults -potentially Inappropriate Medication (PIM) use in older adults due to medication-disease or medication-syndrome interactions that may exacerbate the disease or syndrome -medications to be used cautiously in older adults -clinically significant drug interactions that should be avoided in older adults -medications to be avoided or dosage decreased in the presence of impaired kidney function in older adults
Metabolism Interaction
Correct Answer:
concentration of the medication after biotransformation into active and inactive metabolites in higher or lower than expected. 3 / 4
prescriptive authority
Correct Answer:
refers to the nurse practitioner's authority to prescribe medications.
Full-practice scope
Correct Answer:
Nurse practitioners have the autonomy to evaluate patients, diagnose, order and interpret tests, initiate and manage treatments and prescribe medications, including controlled substances without physician oversight.
Reduced-practice scope
Correct Answer:
Nurse practitioners are limited in at least one element of practice. The state requires a formal collaborative agreement with an outside health discipline for the nurse practitioner to provide patient care.
Restricted practice scope
Correct Answer:
Nurse practitioners are limited in at least one element of practice by requiring supervision, delegation, or team management by an outside health discipline for the nurse practitioner to provide patient care.
Opioids
Correct Answer:
any drug, natural or synthetic, that has actions similar to those of morphine
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