MN553 Unit 6 Quiz Latest Update 2025-2026 150 Questions and 100% Verified Correct Answers Guaranteed A+
A painful inflammatory condition of the external auditory canal - CORRECT ANSWER: Otitis externa
Action for policy and practice - CORRECT ANSWER: Implement at least one policy or practice to improve antibiotic prescribing assess whether it is woking and modify as needed
ADRs of Fluoroquinolones - CORRECT ANSWER: Black box warning- avoid when less
toxic alternatives available
Tendon rupture- older adults at higher risk -Can have delayed onset 120 days to months after administration
Aminopenicillin sensitivity - CORRECT ANSWER: Greater activity against gram-
negative bacteria because of enhanced ability to penetrate the outer membrane organisms
Antibiotic choices for pneumonia in children over 5 years - CORRECT ANSWER:
•Azithromycin: 10 mg/kg on day 1 and 5 mg/kg on days 2 through 5
•Clarithromycin: 15 mg/kg per day in two divided doses (maximum 1 g/day)
•Erythromycin: 40 to 50 mg/kg/day
Antibiotic choices for pneumonia in children under 5 years - CORRECT ANSWER:
Bacterial pneumonia
•Amoxicillin: 80 to 90 mg/kg/day 1 / 4
•Ceftriaxone: 50 mg/kg/day until able to take oral antibiotics
•Penicillin allergy: clindamycin or a macrolide
Infant with suspected chlamydial pneumonia •Azithromycin 20 mg/kg/day for 3 days OR erythromycin (EryPed) 50 mg/kg for 14 days
Antibiotic choices for sinusitis - CORRECT ANSWER: •Amoxicillin first line
•Dose at 80 to 90 mg/kg/day in high-risk children; 45 mg/kg/day in low-risk children
•Adults: 500 mg 3 times/day, or
•High-dose Augmentin
•For penicillin-allergic patients
•Children: cefdinir, cefuroxime, or cefpodoxime
•Adults: doxycycline or respiratory fluoroquinolone (levofloxacin)
Antimycobacterials clincal use - CORRECT ANSWER: Follow CDC guidelines
Active TB requires 4 drug therapy
Preventative therapy includes INH
Antimycobacterials drug interactions - CORRECT ANSWER: MANY
Rifampin: an inducer of CYP450 enzyme
Antimycobacterials/TB cross resistance - CORRECT ANSWER: Cross-resistance with
INH and ethionamide 2 / 4
Antimycobacterials/TB pharmacodynamics - CORRECT ANSWER: •Isoniazid (INH) and
ethambutol inhibit synthesis of mycolic acids.
•Rifampin binds to the beta subunit of mycobacterial DNA-dependent RNA polymerase and inhibits RNA synthesis.
Ethambutol inhibits synthesis of arabinogalactan, an essential component of mycobacteriacell walls.
Antiviral clinical uses - CORRECT ANSWER: Varicella (chickenpox)
Gingivostomatitis in children
Bell's palsy
Antiviral pharmacodynamics - CORRECT ANSWER: Must either block entry into the
cells or be active inside host cells to be effective
Acyclovir: active against herpes simplex viruses 1 and 2 (HSV-1 and HSV-2); varicella- zoster virus (VZV); Epstein-Barr virus (EBV), cytomegalovirus (CMV), and herpes virus 6
Valacyclovir: converted to acyclovir after oral administration and is active against the same viruses
•Famciclovir: active against HSV-1 and HSV-2, VZV, EBV, and hepatitis B virus
•Ganciclovir: active against CMV
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Antiviral Rational drug selection - CORRECT ANSWER: Choice based on cost and
convenience
Antivirals for Hep C - CORRECT ANSWER: •Joint guidelines for treatment by American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (ISDA)
•Treatment of HCV infection based on the genotype and stage of the disease
Antivirals for influenza pharmacodynamics - CORRECT ANSWER: Oseltamivir
(Tamiflu), peramivir (Rapivab), zanamivir (Relenza) are used to treat influenza A and B.
Sensitivity varies by year
•Resistance to amantadine and rimantadine is common, so these drugs are no longer recommended for influenza.
Antivirals: Nucleoside Analogues ADRs - CORRECT ANSWER: •Acyclovir/valacyclovir: few ADRs when given orally
•Valacyclovir: may cause thrombocytopenia purpura, hemolytic uremic syndrome in immunocompromised patients
•Famciclovir may cause dizziness/confusion
AOM antibiotic choice - CORRECT ANSWER: •Amoxicillin first choice, or
•Amoxicillin/clavulanate 90 mg/kg/day •
•Acute Otitis Externa:
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