Mosbys Review for the Pharmacy Technician

Mosby’s Review for the Pharmacy Technician Certification Examination 3rd Edition Mizner Test Bank

Chapter 01: Pharmacology for Technicians

Test Bank

MULTIPLE CHOICE

• Which of the following layers of the heart would be found on the outside?
• Myocardium
• Endocardium
• Epicardium
• Atrium

ANS: C

The epicardium, with the prefix epi-, would be found on the outermost layer, just as the epidermis is the outermost layer of skin. The myocardium is the middle layer, and the endocardium is the inner layer. The atrium is not a layer of the heart but a chamber.

PTS: 1 DIF: Cognitive Level 1: Knowledge REF: p. 12

• A patient takes pseudoephedrine (Sudafed) for nasal congestion; however, the patient has high

blood pressure. This would be considered a drug– interaction.

• food
• disease
• laboratory
• nutrient

ANS: B

Pseudoephedrine (Sudafed) cNanU iRncS rIeaN seGthT eBh.eaCrtO rMate and would not be recommended for patients with high blood pressure; therefore, this combination would represent a drug–disease interaction.

PTS: 1 DIF: Cognitive Level 1: Knowledge REF: p. 17

• A patient overdoses on an opiate, and naloxone (Narcan) is given as an antidote to combat the

effects of the opiate. Naloxone would then be considered a(n):

• antagonist.
• agonist.
• sympathomimetic.
• anxiolytic.

ANS: A

Antagonists can block the effects of another drug. Agonists affect the receptors and activate them. A sympathomimetic mimics the sympathetic nervous system, and anxiolytics stop anxiety symptoms.

PTS: 1 DIF: Cognitive Level 3: Application REF: p. 17

• Augmentin is a combination of amoxicillin and clavulanic acid. Clavulanic acid prevents the

degradation of amoxicillin by -lactamases. Clavulanic acid thus serves to the effects of amoxicillin.

• denature 1 / 4

• degrade
• reduce
• potentiate

ANS: D

Clavulanic acid increases or potentiates the effect of amoxicillin against bacteria, -lactamases, or enzymes that can degrade amoxicillin. All of the other choices indicate that clavulanate reduces the effectiveness of amoxicillin, which is not correct.

PTS: 1 DIF: Cognitive Level 3: Application REF: p. 17

• When two drugs are combined and said to be “synergistic,” these drugs together would be

effective.

• less
• more
• just as
• None of the above is correct.

ANS: B

When something is synergistic, there is more effectiveness from the combination of the products.

PTS: 1 DIF: Cognitive Level 1: Knowledge REF: p. 17

• In which pregnancy category have animal or human studies shown fetal abnormalities or

toxicity and the risk outweighs the benefits?

• A
• B
• C
• X

ANS: A

In pregnancy, category X animal or human studies have shown fetal abnormalities or toxicity, and the risk outweighs the benefits. Category A is the safest of the categories.

PTS: 1 DIF: Cognitive Level 1: Knowledge REF: p. 17

• Which of the following is the best definition for a brand name?
• Assigned by the drug manufacturer and is protected through a patent
• Determined by chemical structure of the drug entity
• Assigned to a medication and contains a word stem that has been issued by the

U.S. Adopted Names Council

• Determined by the botanical origin of the drug entity

ANS: A

A proprietary, brand, or trade name is assigned by the drug manufacturer and is protected through a patent. The chemical name is determined by chemical structure of the drug entity, and the nonproprietary (generic) name is assigned to a medication and contains a word stem that has been issued by the U.S. Adopted Names Council.

PTS: 1 DIF: Cognitive Level 1: Knowledge REF: p. 18 2 / 4

• Which of the following is the best definition for a generic name?
• Assigned by the drug manufacturer and is protected through a patent
• Determined by chemical structure of the drug entity
• Assigned to a medication and contains a word stem that has been issued by the

U.S. Adopted Names Council

• Determined by the botanical origin of the drug entity

ANS: C

A proprietary, brand, or trade name is assigned by the drug manufacturer and is protected through a patent. The chemical name is determined by chemical structure of the drug entity, and the nonproprietary (generic) name is assigned to a medication and contains a word stem that has been issued by the U.S. Adopted Names Council.

PTS: 1 DIF: Cognitive Level 1: Knowledge REF: p. 18

• Suffixes are often useful in determining the drug class of a medication. Which of the

following suffixes is correctly matched to its drug class?

a. -prazole: Proton pump inhibitor for acidic conditions

b. -vastatin: H2-blocker for acidic conditions

c. -pril: Cholesterol-lowering medication

d. -tidine: ACE inhibitor

ANS: A

The following drug suffixes are matched to their drug classes:

-prazole: Proton pump inhibitor for acidic conditions

-vastatin: Cholesterol lowering medication

-pril: ACE inhibitor

-tidine: H2-blocker for acidNicU

cRonS dIitiN onGsT B.C O M PTS: 1 DIF: Cognitive Level 1: Knowledge REF: p. 18

• Ranitidine (Zantac) and loratadine (Claritin) have very similar suffixes, yet are very different

in their pharmacologic function. What is the difference?

• Both are antihistamines, but one affects acid and the other allergies.
• Loratadine (Claritin) is for acidic conditions, and ranitidine (Zantac) is for allergic

conditions.

• Ranitidine (Zantac) is nonsedating, but loratadine (Claritin) is very sedating.
• Both are antihistamines, and there is no difference in their effects.

ANS: A

Whereas ranitidine (Zantac) is an H2-blocker that reduces stomach acid, loratadine (Claritin) is an H1-blocker that alleviates allergy symptoms. Loratadine is nonsedating.

PTS: 1 DIF: Cognitive Level 3: Application REF: pp. 72-73

• All of the following are ways a patient might distinguish the classes of the medications

nystatin (Mycostatin) and atorvastatin (Lipitor) except which of the following?

• Both have the ending –statin.
• The ending that indicates cholesterol lowering is -vastatin, to which nystatin does

not conform.

• Myco- is a prefix that means fungus. 3 / 4

U S N T O

• Lipi- is one letter short of lipid, and cholesterol is a type of lipid.

ANS: A

Although Lipitor is often referred to as a “statin,” both drugs have the same suffix yet are for very different conditions. By using -vastatin as the baseline or the prefixes myco- or lipi-, one can determine the medication’s class.

PTS: 1 DIF: Cognitive Level 3: Application REF: p. 18

• Which of the following drug interactions is correctly matched to its definition?
• Addition: The combined effect of two drugs; it is equal to the sum of the effects of

each drug taken alone

b. Antagonism: The joint action of drugs in which their combined effect is more

intense or longer in duration than the sum of the effects of two drugs

c. Potentiation: One drug works against the action of another drug

• Synergism: One drug increases or prolongs the effect of another drug; the total

effect is greater than the sum of the effects of each drug alone

ANS: A

The definitions below are correctly matched:

Addition: The combined effect of two drugs; it is equal to the sum of the effects of each drug taken alone

Antagonism: One drug works against the action of another drug

Potentiation: One drug increases or prolongs the effect of another drug; the total effect is greater than the sum of the effects of each drug alone (e.g., Vistaril and Demerol) Synergism: The joint action of drugs in which their combined effect is more intense or longer in duration than the sum of the effects of two drugs

N R I G B.C M

PTS: 1 DIF: Cognitive Level 1: Knowledge REF: p. 17

• Prefixes are often useful in determining the drug class of a medication. Which of the

following prefixes is correctly matched to its drug class?

a. sulfa-: Sulfonamide antibiotic

b. ceph- or cef-: Estrogen

c. estr-: Cephalosporin antibiotic

d. profen-: Antiinflammatory

ANS: A

The following drug prefixes are matched to their drug classes:

sulfa-: Sulfonamide antibiotic

ceph- or cef-: Cephalosporin antibiotic

estr-: Estrogen

Although -profen would be matched correctly to an antiinflammatory, it is a suffix, not a prefix.

PTS: 1 DIF: Cognitive Level 1: Knowledge REF: pp. 18-19

• Which of the following mechanisms of action is correctly matched to its antibiotic class?
• Penicillins prevent bacteria from forming a cell wall.
• Sulfonamides inhibit protein synthesis in bacteria by binding ribosomes.
• Cephalosporins interfere with folic acid formation.
• / 4