NBME CBSE REAL EXAM QUESTIONS AND ANSWERS
LATEST COMPLETE EXAM
- Which of the following is the most common site of metastasis for colorectal
cancer?
- Liver
- Lungs
- Brain
- Bone
Answer: A) Liver
Rationale: Colorectal cancer most commonly metastasizes to the liver because
the venous blood from the colon drains into the portal circulation, which leads directly to the liver.
- Which of the following hormones is primarily responsible for the regulation of
calcium homeostasis?
- Thyroxine
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- Parathyroid hormone
- Insulin
- Cortisol
Answer: B) Parathyroid hormone
Rationale: Parathyroid hormone (PTH) is the primary regulator of calcium levels
in the blood. It increases calcium reabsorption from the kidneys and mobilizes calcium from bones.
- A 45-year-old woman presents with a history of fatigue, cold intolerance, and
weight gain. Physical examination shows dry skin, bradycardia, and delayed deep tendon reflexes. Laboratory findings reveal an elevated TSH level and low free T4.What is the most likely diagnosis?
- Hyperthyroidism
- Hypothyroidism
- Adrenal insufficiency
- Pituitary adenoma
Answer: B) Hypothyroidism 2 / 4
Rationale: The elevated TSH with low free T4 indicates primary hypothyroidism.
Symptoms like fatigue, cold intolerance, and weight gain are common in hypothyroid patients.
- A 22-year-old male presents with severe abdominal pain, nausea, and vomiting.
On examination, his abdomen is distended, and there is absent bowel sounds.Imaging reveals a "double-bubble" sign. What is the most likely diagnosis?
- Intussusception
- Pyloric stenosis
- Duodenal atresia
- Hirschsprung disease
Answer: C) Duodenal atresia
Rationale: The "double-bubble" sign on imaging is characteristic of duodenal atresia, which is a congenital obstruction of the duodenum.
- In the process of oxidative phosphorylation, the electron transport chain
primarily occurs in which part of the mitochondria?
- Inner mitochondrial membrane
- Outer mitochondrial membrane 3 / 4
- Mitochondrial matrix
- Cristae
Answer: A) Inner mitochondrial membrane
Rationale: The electron transport chain (ETC) occurs in the inner mitochondrial
membrane, where electrons are passed through protein complexes to ultimately produce ATP.
- Which of the following enzymes is involved in the breakdown of glycogen to
glucose?
- Glycogen synthase
- Hexokinase
- Glycogen phosphorylase
- Phosphofructokinase
Answer: C) Glycogen phosphorylase
Rationale: Glycogen phosphorylase is the enzyme that breaks down glycogen
into glucose-1-phosphate during glycogenolysis.
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