NR 507 midterm Exam (Latest 2024/ 2025 Update) Advanced Pathophysiology | Questions and Verified Answers| 100% Correct |Grade A – Chamberlain
Hives (urticaria) are an example of a: - ANSWER
Type 1 hypersensitivity reaction.Anaphylaxis is what type of reaction? - ANSWER type 1 hypersensitivity Which of the following are considered the "first responders" of the innate immune system? - ANSWER neutrophils Allergic contact dermatitis is an example of what type of hypersensitivity reaction. - ANSWER type
- hypersensitivity reaction
Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: -
ANSWER IgG or IgM 1 / 4
Type 1 hypersensitivity reaction is mediated by - ANSWER IgE Allergic asthma is an example of - ANSWER type 1 hypersensitivity reaction type 2 hypersensitivity - ANSWER tissue specific Primary effector cells of type 2 - ANSWER macrophages Examples of type 2 reactions - ANSWER drug allergies, hemolytic anemia, blood transfusion mismatch, allergies against infectious agents Type 2 causes - ANSWER The cell to be destroyed by the antibody Cell destruction through phagocytosis by macrophages Damage to the cell by neutrophils triggering phagocytosis Natural killer cells to release toxic substances that destroy the target cell Malfunction of the cell without destruction 2 / 4
Type 3 hypersensitivity reaction - ANSWER antigen-antibody response Where does the antibody bind to the antigen in type 3 response? - ANSWER in blood or body fluids and then circulates to tissue Where does the antibody bind to the antigen in type 1, 2, and 4? - ANSWER on cell surface Primary effector cell in type 3 - ANSWER neutrophils example of type 3 reaction - ANSWER serum sickness type 4 hypersensitivity reaction - ANSWER cell-mediated response primary mediators of type 4 - ANSWER lymphocytes and macrophages 3 / 4
type 4 mediated by - ANSWER T lymphocytes and do not use antibodies example of type 4 - ANSWER localized contact dermatitis (poison ivy)
Damage occurs with ABO incompatibility because: - ANSWER
Complement damages RBC membrane causing cell lysis.Which of the following is the underlying pathology for hay fever? - ANSWER mast cell degranulation The diagnosis for an individual who presents to the office with sudden swollen lips and eyes, shortness of breath and throat tightness after a bee
sting is: - ANSWER anaphylaxis
Which of the following assessment findings would be expected in a patient who presents with urticaria? - ANSWER Eosinophilia.
- / 4