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NR 566 MID-TERM/ NR566 ADVANCED PHARMACOLOGY
FOR CARE OF THE FAMILY MIDTERM EXAM NEWEST 2025
TEST BANK| COMPLETE 300 QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSW ERS) ALREADY
GRADED A+|| BRAND NEW!!
What antibiotics can be prescribed SAFELY throughout pregnancy? - ANSWER - penicillin's, cephalosporins, erythromycin
Second line treatment for CAP (if amoxicillin doesn't work) - ANSWER
- Respiratory fluoroquinolone
The patient was treated with an antibiotic in the last 90 days of contracting CAP what type of antibiotics should be prescribed? - ANSWER - quinolone (ex. fluoroquinolone)
Tendonitis/tendon rupture is highly associated with which antibiotic class? - ANSWER - fluoroquinolone (why they should be avoided in pregnancy)
Anthelmintic safe for pregnancy - ANSWER - Praziquantel
anthelmintic's safe for breastfeeding - ANSWER - Mebendazole pyrantel pamoate
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pg. 2 anthelmintic's caution with breastfeeding/pregnancy - ANSWER - albendazole ivermectin diethylcarbamazine
Risks with didanosine - ANSWER - lactic acidosis, severe hepatomegaly with steatosis, severe pancreatitis
Voriconazole (-azoles) should NOT be combined with what - ANSWER
- drugs that are P450 inducers (Phenobarbital), reduce levels of
Voriconazole
What is Enterobius vermicularis? - ANSWER - Pinworm infestation (Nematode) Most common in US pinworms in ileus and large intestine symptoms - perianal itching and sleep disturbance Once itching/on hands can spread through touching
Who would you expect to have Enterobius vermicularis? - ANSWER - Primarily in children (spread through daycares/schools)
How to treat Enterobius vermicularis? - ANSWER - Medication:
albendazole, mebendazole, pyrantel pamoate Hand washing, all family members should be treated at same time 2 / 4
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pg. 3 Monitoring needs for long term antifungal use - ANSWER - Liver function - AST, ALT, alkaline phosphate, and bilirubin
How to treat systemic fungal infections - ANSWER - Treating systemic
mycoses can be difficult: these infections often resist treatment and
hence may require prolonged therapy with drugs that frequently prove toxic.Aspergillosis - voriconazole candidiasis- amphotericin B or fluconazole plus or minus flucytosine Histoplasmosis- amphotericin B or itraconazole
adverse effects of abacavir - ANSWER - Lactic acidosis, a severe hepatomegaly with steatosis
risks with saquinavir - ANSWER - Use caution in patients with structural heart dx, cardiac conduction disturbances, and ischemic heart disease and taking other drugs that prolong PR interval
How to measure success with antiretroviral therapy for HIV - ANSWER
- reduction in plasma HIV RNA
What does an increase in CD4 indicate? - ANSWER - increase in CD4, reduction in viral load indicating restoration of immune function
When do use foscarnet in HIV+ patients? - ANSWER - Used to treat cytomegalovirus (CMV) and CMV-related ophthalmic retinitis in 3 / 4
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pg. 4 individuals with AIDs and who have been unable to tolerate gancyclovir.Also approved for use in immunocompromised patients with HSV with resistance to acyclovir. "It has no use in treating HIV because it does it does not have antiretroviral properties" (NIH)
PR interval impacts use of which HIV drugs - ANSWER - atazanavir, saquinavir, lopinavir, ritonavir
Metronidazole patient teaching - ANSWER - do not take with alcohol to prevent a disulfiram-like reaction
mechanism of action with antihistamines - ANSWER - H1 blockers bind selectively to H1-histaminic receptors, thereby blocking the actions of histamine at these sites. These drugs can relieve sneezing, rhinorrhea, and nasal itching; however, they do not reduce nasal congestion.
cromolyn mechanism of action - ANSWER - Suppresses release of histamine and inflammatory mediators from mast cells
therapeutic action of guaifenesin - ANSWER - expectorant - thins secretions and loosens mucous
patient education needed for isotretinoin (Accutane) - ANSWER - protect skin from sunlight, avoid sunlamps and tanning beds pregnancy should be avoided, and two reliable birth control methods used risk for depression and suicide
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