pg. 1 NR507 Advanced Exam, Questions with Correct Verified Answers. Updated 2024-2025 Graded A+
Anemia Answer - Reduction in the proportion of red blood cells
Hemoglobin of a man with anemia Answer - <13.5 g/dL
Hemoglobin of a woman with anemia Answer - < 12g/dL
What stimulates erythropoiesis Answer - hypoxia
Reticulocytes Answer - Baby RBCs, that are the first RBCs to leave the bone marrow and enter into circulation for about two days before maturing into mature RBCs
How are reticulocyte counts useful Answer - These counts increase with blood loss, or when blood cells are destroyed, such as in hemolytic anemia.Depends on health of bone marrow, so if there is anemia, and the reticulocyte count is normal or less than normal that can indicate bone marrow dysfunction or suppression Functions of RBCs
Answer - Carry oxygen from the lungs to tissues • Transport CO2 • Electrolytes, hormones, vitamins, antibodies, heat, immune cells 1 / 4
pg. 2 MCV Answer - cell size
MCHC Answer - mean cell hemoglobin concentration • Cell color
Microcytic anemia Answer - MCV <80
Normocytic anemia Answer - MCV 80-100
macrocytic anemia Answer - MCV > 100
hypochromic anemia Answer - MCHC <33
Hyperchromic Answer - MCHC > 37
RDW% Answer - Variation in cell size
Anemia is not a disease but a Answer - A presentation of an underlying illness
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pg. 3 Causes of microcytic anemia -Iron deficiency anemia -Copper deficiency -Thalassemia -Hemolysis -Lead poisoning -Inflammation -Sideroblastic anemia -Anemia of chronic disease
Common findings in microcytic anemia -Circulating RBCs are smaller than the usual side of RBCs (microcytic) -They are often decreased in their red color (hypochromic) because of a defective heme synthesis -MCV <80 -MCHC <33
Iron An essential element for a blood production Recycled in conserved by the body Necessary to produce him Diurnal
Ferritin -Storage form of iron (apo-protein) -About 25% of iron is stored as this -Acute phase reactant
normal iron level Answer - 50-150 mcg/dL 3 / 4
pg. 4 Normal TIBC Answer - 250-450 mcg/dL
Normal % saturation ferritin Answer - 20-50%
Normal ferritin levels v13-150ng/ml
Iron transports via Answer - Transferrin
What can falsely elevated ferritin?Answer - Widespread inflammation
IDA Causes
Blood loss:
GI ulcerations, malignancies, menorrhagia, milk-anemia [infants]
Malabsorptions:
Gastric resection, Celiac, Inflammatory disorders
Symptoms of IDA Fatigue Exercising tolerance, SON Headache Difficulty concentrating Pallor Chest pain (severe anemia, Hgb<7)
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