NR565 ADVANCED PHARMACOLOGY
LATEST EXAM 2024/2025 WITH QUESTIONS
AND WELL VERIFIED ANSWERS [GRADED
A+] DETAILED ANSWERS // NR565
What constitutes a drug resistant TB? - ANSWER-TB bacteria become resistant to the drugs used to treat the disease and includes multidrug-resistant (MDR TB) and extensively drug-resistant (XDR TB).
Examples of decongestants - ANSWER-Beclomethasone dipropionate Budesonide Fluticasone Triamcinolone
Which anti-diarrheal medication is contradicted in children during or after chickenpox and is associated with gray/black stools and black tongue? - ANSWER-Bismuth subsalicylate (Pepto Bismol)
Why should a patient keep a diary in the aid of diagnosis and treatment of IBS? - ANSWER-Patients should keep a log to identify foods and stressors that trigger symptoms
1st line treatment for gastroparesis? - ANSWER-Metoclopramide is recommended first line for N/V due to gastroparesis
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Metoclopramide concerns - ANSWER-Long-term high-dose therapy can cause irreversible tardive dyskinesia, characterized by repetitive, involuntary movements of the arms, legs, and facial muscles.
Which drug class for cough and cold has no significant drug interactions? - ANSWER-Expectorants
What contraindications are you looking for when prescribing a decongestant? - ANSWER-known drug allergy, narrow-angle glaucoma, uncontrolled cardiovascular disease, hypertension, diabetes, hyperthyroidism and prostatitis
Isoniazid (INH) - ANSWER-primary treatment of TB and can be used to prevent TB in people that have been exposed
treatment of TB in a pregnant person - ANSWER-Rifabutin is deemed the safest during pregnancy
nicotine replacement how it works? - ANSWER-helps with withdraws from nicotine
Nicotine gum education - ANSWER-The most common adverse effects are mouth and throat soreness, jaw muscle ache, eructation (belching), and hiccups. Using optimal chewing technique minimizes these problems.
Patients should be advised to chew the gum slowly and intermittently for approximately 30 minutes. Rapid chewing can release too much nicotine at one time, resulting in effects similar to those of excessive smoking (e.g., nausea, throat irritation, hiccups). Because foods and beverages can reduce nicotine absorption, patients should not eat or drink while chewing or for 15 minutes before chewing.Not recommended over 6 months. Wellbutrin Contraindications for smoking 2 / 3
cessation - ANSWER-should be used in caution with patients that have history of psychiatric disease .What labs are used to diagnose thyroid function? - ANSWER-1. Serum thyroid- stimulating hormone test (TSH)
- Serum thyroxine test (Total or Free T4)
- Serum triiodothyronine test (Total or Free T3)
s/s hypothyroidism - ANSWER-Signs and symptoms of hypothyroidism depend on disease severity. The face is pale, puffy, and expressionless; skin is cold and dry; hair is brittle; hair loss occurs;Heart rate and temperature are lowered. The patient may complain of lethargy, fatigue, and intolerance to cold. Mentation may be impaired.
s/s hyperthyroidism - ANSWER-Exophthalmos; Heartbeat is rapid and strong; dysrhythmias and angina may develop; nervousness; insomnia, rapid thought flow; rapid speech; Skeletal muscles may weaken and atrophy; Metabolic rate is raised, resulting in increased heat production, increased body temperature, intolerance to heat, and skin that is warm and moist. Appetite is increased, but weight loss may still occur.
When should you re-check labs after initiating Levothyroxine? - ANSWER-TSH 6-8 weeks after initiation or dose changes.
S/S of Thyrotoxic Crisis (Thyroid Storm) - ANSWER-profound hyperthermia (105°F or even higher), severe tachycardia, restlessness, agitation, and tremor.Unconsciousness, coma, hypotension, and heart failure may occur *Excessive levels of thyroid hormones (occurs after surgery or intercurrent illness (e.g. sepsis)
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